Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | HPGD | P15428 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.43 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.43 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28743589 | 0.80 | PDE4B (0.53) | ALDH1A1KDM4EHPGDKMT2AHTT | |
| SCHEMBL29520539 | 0.78 | PDE5A (0.39) | ALDH1A1KDM4EHPGDKMT2AHTT | |
| SCHEMBL15631894 | 0.78 | ALDH1A1 (0.76) | GAAALDH1A1KDM4EHPGDKMT2A | |
| SCHEMBL29427445 | 0.75 | GAA (0.55) | GAAALDH1A1KDM4EHPGDKMT2A | |
| SCHEMBL13791090 | 0.74 | GAA (0.54) | GAAALDH1A1KDM4EHPGDKMT2A | |
| SCHEMBL15623056 | 0.73 | GAA (0.56) | GAAALDH1A1KDM4EHPGDKMT2A | |
| SCHEMBL19100171 | 0.72 | RPS6KA5 (0.41) | KDM4ESMN1; SMN2 | |
| SCHEMBL30725494 | 0.72 | MAP2K4 (0.41) | ALDH1A1KDM4EPOLBL3MBTL1 | |
| SCHEMBL16653684 | 0.72 | MAP2K4 (0.41) | ALDH1A1KDM4EPOLBL3MBTL1 | |
| SCHEMBL18953236 | 0.71 | TSHR (0.51) | GAAALDH1A1KDM4EHPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114555585-A | HPK1 inhibitors and uses thereof | 上海齐鲁锐格医药研发有限公司 | 2022-05-27 | — | — | CN | disclosed |