Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F11 | P03951 | 3/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.50 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | MDM2 | Q00987 | 3/20 | 0.47 |
| ▸ | XDH | P47989 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29565494 | 1.00 | F11 (0.66) | F11CYP1A2KDM4ELMNAHTT | |
| SCHEMBL28746545 | 0.86 | MAOB (0.50) | F11CYP1A2KDM4ELMNAHTT | |
| SCHEMBL27895954 | 0.83 | CYP1A2 (0.78) | F11CYP1A2KDM4EALDH1A1PKM | |
| SCHEMBL28746466 | 0.83 | TRPM8 (0.53) | F11CYP1A2KDM4ELMNAHTT | |
| SCHEMBL29565728 | 0.83 | TRPM8 (0.53) | F11CYP1A2KDM4ELMNAHTT | |
| SCHEMBL28746452 | 0.82 | CYP1A2 (0.58) | F11CYP1A2KDM4ELMNAALDH1A1 | |
| SCHEMBL25326934 | 0.80 | F11 (1.00) | F11CYP1A2ALDH1A1PKMPIN1 | |
| SCHEMBL29565288 | 0.80 | F11 (1.00) | F11CYP1A2ALDH1A1PKMPIN1 | |
| SCHEMBL26108969 | 0.76 | F11 (0.57) | F11CYP1A2ALDH1A1PKMKMT2A | |
| SCHEMBL26108278 | 0.74 | F11 (0.55) | F11CYP1A2ALDH1A1PKMPIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114539158-B | FXIa inhibitor compound and preparation method and application thereof | 沈阳药科大学 | 2023-12-08 | — | — | CN | disclosed |
| CN-114539158-A | FXIa inhibitor compound and preparation method and application thereof | 沈阳药科大学 | 2022-05-27 | — | — | CN | disclosed |