Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 2/20 | 0.44 |
| ▸ | F11 | P03951 | 13/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.38 |
| ▸ | CTSA | P10619 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29565437 | 1.00 | KMO (0.44) | KMOF11NOTUMMDM2CTSA | |
| SCHEMBL29565504 | 0.86 | MAPK1 (0.42) | F11 | |
| SCHEMBL28746455 | 0.86 | MAPK1 (0.42) | F11 | |
| SCHEMBL29565445 | 0.83 | F11 (0.52) | KMOF11 | |
| SCHEMBL28746450 | 0.83 | F11 (0.52) | KMOF11 | |
| SCHEMBL29565531 | 0.80 | KMO (0.44) | KMOF11NOTUMMDM2CTSA | |
| SCHEMBL28746448 | 0.80 | KMO (0.44) | KMOF11NOTUMMDM2CTSA | |
| SCHEMBL29565489 | 0.73 | F11 (0.48) | F11 | |
| SCHEMBL28746474 | 0.73 | MAPK1 (0.43) | F11 | |
| SCHEMBL28746444 | 0.73 | F11 (0.48) | F11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114539158-B | FXIa inhibitor compound and preparation method and application thereof | 沈阳药科大学 | 2023-12-08 | — | — | CN | disclosed |
| CN-114539158-A | FXIa inhibitor compound and preparation method and application thereof | 沈阳药科大学 | 2022-05-27 | — | — | CN | disclosed |