Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F11 | P03951 | 17/20 | 0.52 |
| ▸ | KMO | O15229 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29565445 | 1.00 | F11 (0.52) | F11KMOCYP1A2 | |
| SCHEMBL28746453 | 0.86 | LMNA (0.51) | F11CYP1A2 | |
| SCHEMBL29565489 | 0.84 | F11 (0.48) | F11CYP1A2 | |
| SCHEMBL28746444 | 0.84 | F11 (0.48) | F11CYP1A2 | |
| SCHEMBL29565437 | 0.83 | KMO (0.44) | F11KMO | |
| SCHEMBL29565531 | 0.83 | KMO (0.44) | F11KMO | |
| SCHEMBL28746448 | 0.83 | KMO (0.44) | F11KMO | |
| SCHEMBL28746486 | 0.83 | KMO (0.44) | F11KMO | |
| SCHEMBL29565494 | 0.72 | F11 (0.66) | F11CYP1A2 | |
| SCHEMBL28746452 | 0.71 | CYP1A2 (0.58) | F11CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114539158-B | FXIa inhibitor compound and preparation method and application thereof | 沈阳药科大学 | 2023-12-08 | — | — | CN | disclosed |
| CN-114539158-A | FXIa inhibitor compound and preparation method and application thereof | 沈阳药科大学 | 2022-05-27 | — | — | CN | disclosed |