SCHEMBL28746513

SCHEMBL28746513

CN1C(=O)C(C)(CS(=O)(=O)O)c2cccc(-c3ccccc3)c21

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 1/20 0.35
SLC6A4 P31645 1/20 0.35
SLC6A3 Q01959 1/20 0.35
ALDH1A1 P00352 5/20 0.35
MAPT P10636 2/20 0.35
PLIN1 O60240 1/20 0.35
PLIN5 Q00G26 1/20 0.35
ABHD5 Q8WTS1 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
PKM P14618 1/20 0.34
SLC9A1 P19634 1/20 0.34
NPC1 O15118 1/20 0.33
SCN1A P35498 1/20 0.33
SCN2A Q99250 1/20 0.33
SCN3A Q9NY46 1/20 0.33
RAD52 P43351 1/20 0.33
PGR P06401 1/20 0.33
AGTR1 P30556 1/20 0.32
LIPG Q9Y5X9 1/20 0.32
CYP1A2 P05177 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28941315 0.99 ALDH1A1 (0.34) SLC6A2SLC6A4SLC6A3ALDH1A1MAPT
SCHEMBL29566224 0.85 MAPT (0.34) SLC6A2ALDH1A1MAPTPLIN1PLIN5
SCHEMBL28250861 0.77 PGR (0.46) SLC6A2SLC6A4SLC6A3ALDH1A1MAPT
SCHEMBL28746565 0.76 MAPT (0.38) ALDH1A1MAPTCYP1A2CYP2D6CYP2C9
SCHEMBL28746528 0.76 RAD52 (0.49) ALDH1A1MAPTPKMRAD52
SCHEMBL28746505 0.75 MAPT (0.38) ALDH1A1MAPTCYP1A2CYP2D6CYP2C9
SCHEMBL28342990 0.69 PGR (0.41) ALDH1A1MAPTPGR
SCHEMBL28746487 0.68 ALDH1A1 (0.46) ALDH1A1
SCHEMBL28746561 0.67 ALDH1A1 (0.57) ALDH1A1MAPT
SCHEMBL28746498 0.67 PGR (0.33) PGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114539121-A A novel, photo-promoted process for the preparation of sulfonates and sulfonamides from sulfonyl chlorides 天津师范大学 2022-05-27 CN disclosed