SCHEMBL28746487

SCHEMBL28746487

CC1(CS(=O)(=O)O)C(=O)N2CCCc3cccc1c32

nearest known ligand 0.46

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.46
GAA P10253 1/20 0.46
MAP2K1 Q02750 1/20 0.45
CES1 P23141 2/20 0.45
USP2 O75604 1/20 0.45
CHRM2 P08172 1/20 0.36
ADRA2A P08913 1/20 0.36
ALOX12 P18054 1/20 0.35
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
KDM4E B2RXH2 1/20 0.34
HPGD P15428 1/20 0.34
HTT P42858 1/20 0.34
RAB9A P51151 1/20 0.34
TSHR P16473 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
HSD17B10 Q99714 1/20 0.34
AR P10275 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29565540 0.86 ALDH1A1 (0.44) ALDH1A1GAAMAP2K1CES1USP2
SCHEMBL6746228 0.71 MAP2K1 (0.53) ALDH1A1GAAMAP2K1CES1USP2
SCHEMBL10366644 0.68 ALDH1A1 (0.51) ALDH1A1GAAMAP2K1CES1USP2
SCHEMBL28746513 0.68 SLC6A2 (0.35) ALDH1A1
SCHEMBL10860119 0.68 ALDH1A1 (0.53) ALDH1A1GAAMAP2K1CES1USP2
SCHEMBL28941315 0.68 ALDH1A1 (0.34) ALDH1A1
SCHEMBL13308993 0.67 ALDH1A1 (0.43) ALDH1A1GAAMAP2K1CES1USP2
SCHEMBL11472180 0.66 SIGMAR1 (0.54) ALDH1A1GAAMEN1KMT2ATSHR
SCHEMBL12721306 0.66 CES1 (0.47) ALDH1A1GAAMAP2K1CES1USP2
SCHEMBL1585025 0.66 CES1 (0.47) ALDH1A1GAAMAP2K1CES1USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114539121-A A novel, photo-promoted process for the preparation of sulfonates and sulfonamides from sulfonyl chlorides 天津师范大学 2022-05-27 CN claimed