SCHEMBL287469

SCHEMBL287469

COC(=O)Cc1ccc(O)c(N)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 6/20 1.00
ALDH1A1 P00352 4/20 1.00
GFER P55789 1/20 1.00
HSP90AB1 P08238 1/20 0.53
CYP4F2 P78329 1/20 0.50
CYP4A11 Q02928 1/20 0.50
SLC7A5 Q01650 1/20 0.47
TSHR P16473 4/20 0.46
TDP1 Q9NUW8 3/20 0.46
NFKB1 P19838 3/20 0.46
MAPT P10636 4/20 0.46
HPGD P15428 4/20 0.46
YWHAG P61981 1/20 0.45
TLR7 Q9NYK1 3/20 0.45
KDM4E B2RXH2 3/20 0.44
BLM P54132 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
MEN1 O00255 1/20 0.44
THRB P10828 1/20 0.44
RECQL P46063 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL11216073 0.98 GAA (0.97) GAAALDH1A1GFERHSP90AB1CYP4F2
SCHEMBL2436585 0.86 GAA (0.76) GAAALDH1A1GFERHSP90AB1CYP4F2
SCHEMBL30565426 0.86 ALDH1A1 (0.75) GAAALDH1A1GFERHSP90AB1CYP4F2
SCHEMBL7237331 0.86 ALDH1A1 (0.75) GAAALDH1A1GFERHSP90AB1CYP4F2
SCHEMBL3668882 0.84 GAA (0.72) GAAALDH1A1GFERHSP90AB1CYP4F2
SCHEMBL29446278 0.84 GAA (0.72) GAAALDH1A1GFERHSP90AB1CYP4F2
SCHEMBL11216725 0.83 ALDH1A1 (0.71) GAAALDH1A1GFERTSHRTDP1
SCHEMBL5656071 0.83 ALDH1A1 (0.71) GAAALDH1A1GFERCYP4F2CYP4A11
SCHEMBL8147823 0.83 ALDH1A1 (0.71) GAAALDH1A1GFERHSP90AB1CYP4F2
SCHEMBL20045098 0.83 ALDH1A1 (0.71) GAAALDH1A1GFERHSP90AB1CYP4F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 94 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4721737-A1 USE OF PHARMACEUTICAL COMPOSITION COMPRISING COMPOUND HAVING BIS(AZANYLYLIDENE) SULFONYL STRUCTURE FOR TREATING ANEMIA-RELATED DISEASES Scinnohub Pharmaceutical Co., Ltd. (CN) 2026-04-08 EP disclosed
US-12565492-B2 Anaplastic Lymphoma Kinase (ALK) degraders and uses thereof TRIANA BIOMEDICINES, INC. (US) 2026-03-03 US disclosed
US-20260042752-A1 ANAPLASTIC LYMPHOMA KINASE (ALK) DEGRADERS AND USES THEREOF TRIANA BIOMEDICINES INC (US) 2026-02-12 US disclosed
EP-3573972-B1 RORGAMMA MODULATORS AND USES THEREOF GENFIT (FR) 2026-01-14 EP disclosed
US-20250145635-A1 COMPOUND CONTAINING BIS(AZANYLYLIDENE) SULFONYL STRUCTURE AND USE THEREOF IN MEDICINE SCINNOHUB PHARMACEUTICAL CO., LTD. (CN) 2025-05-08 US disclosed
WO-2025050125-A1 SUBSTITUTED BENZOXAZOLYLAMINO BENZOXAZOLES IMMVENTION THERAPEUTIX (US) 2025-03-06 WO disclosed
WO-2024245143-A1 USE OF PHARMACEUTICAL COMPOSITION COMPRISING COMPOUND HAVING BIS(AZANYLYLIDENE) SULFONYL STRUCTURE FOR TREATING ANEMIA-RELATED DISEASES 赛诺哈勃药业(成都)有限公司 2024-12-05 WO disclosed
EP-4455136-A1 COMPOUND CONTAINING BIS(AZANYLYLIDENE) SULFONYL STRUCTURE AND USE THEREOF IN MEDICINE Scinnohub Pharmaceutical Co., Ltd. (CN) 2024-10-30 EP disclosed
EP-3573960-B1 N-{[2-(PIPERIDIN-1-YL)PHENYL](PHENYL)METHYL}-2-(3-OXO-3,4-DIHYDRO-2H-1,4-BENZOXAZIN-7-YL)ACETAMIDE DERIVATIVES AND RELATED COMPOUNDS AS ROR-GAMMA MODULATORS FOR TREATING AUTOIMMUNE DISEASES GENFIT (FR) 2023-08-16 EP disclosed
WO-2023116774-A1 COMPOUND CONTAINING BIS(AZANYLYLIDENE) SULFONYL STRUCTURE AND USE THEREOF IN MEDICINE 赛诺哈勃药业(成都)有限公司 2023-06-29 WO disclosed
CN-1121072-A Acetamides MERCK PATENG GES MIT BESCHRANK (DE) 1996-04-24 CN disclosed
US-5472961-A Acetamides MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1995-12-05 US disclosed
US-4943645-A Benzoquinone derivatives and production thereof TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1990-07-24 US disclosed
US-4874752-A INHIBIT COLLAGEN BIOSYNTHESIS TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1989-10-17 US disclosed
US-4808339-A ARTHRITIS, ASTHMA, CIRRHOSIS, RHINITIS TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1989-02-28 US disclosed
US-4751303-A INHIBIT COLLAGEN BIOSYNTHESIS TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1988-06-14 US disclosed
EP-0092136-B1 BENZOQUINONE DERIVATIVES AND PRODUCTION THEREOF Takeda Chemical Industries, Ltd. (JP) 1985-08-28 EP disclosed
US-4526719-A Benzoquinone derivatives and production thereof TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1985-07-02 US disclosed
EP-0092136-A1 Benzoquinone derivatives and production thereof Takeda Chemical Industries, Ltd. (JP) 1983-10-26 EP disclosed
EP-0081321-A1 2-Aminophenol derivatives ONO PHARMACEUTICAL CO., LTD. (JP) 1983-06-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250145635-A1 COMPOUND CONTAINING BIS(AZANYLYLIDENE) SULFONYL STRUCTURE AND USE THEREOF IN MEDICINE BCL9, USP9X, BCL9L GAA 380/4885ALDH1A1 2611/4885GFER 2141/4885
US-20260042752-A1 ANAPLASTIC LYMPHOMA KINASE (ALK) DEGRADERS AND USES THEREOF ALK, NTRK1, NTRK3 GAA 1685/4885ALDH1A1 2403/4885GFER 3720/4885
US-12565492-B2 Anaplastic Lymphoma Kinase (ALK) degraders and uses thereof ALK, NTRK3, NTRK1 GAA 2291/4885ALDH1A1 2387/4885GFER 1722/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.