Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.49 |
| ▸ | BRD4 | O60885 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | PRNP | P04156 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.42 |
| ▸ | BRD2 | P25440 | 3/20 | 0.41 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.41 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.41 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | BTK | Q06187 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1116271 | 0.71 | BRD4 (0.53) | BRD4KDM4EALDH1A1LMNAHPGD | |
| SCHEMBL14562258 | 0.71 | BRD4 (0.73) | ARBRD4BRD2CREBBPATAD2 | |
| SCHEMBL2852978 | 0.70 | BRD4 (0.76) | ARBRD4BRD2CREBBPATAD2 | |
| SCHEMBL4202163 | 0.70 | ALDH1A1 (0.57) | ALDH1A1POLBTSHRALOX15 | |
| SCHEMBL4202164 | 0.70 | ALDH1A1 (0.57) | ALDH1A1POLBTSHRALOX15 | |
| SCHEMBL12885825 | 0.68 | ALDH1A1 (0.69) | KDM4EALDH1A1LMNAPRNPHPGD | |
| SCHEMBL14562268 | 0.68 | AR (0.58) | ARBRD4KDM4EBRD2CREBBP | |
| SCHEMBL27585206 | 0.68 | AR (0.45) | ARBRD4KDM4EALDH1A1HPGD | |
| SCHEMBL31708387 | 0.68 | ALDH1A1 (0.48) | KDM4EALDH1A1LMNAPRNPHPGD | |
| SCHEMBL14677091 | 0.67 | ALOX15 (0.42) | KDM4EALDH1A1LMNAATAD2ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1400973-A | Novel biarylcarboxamides | ASTRAZENECA AB (SE) | 2003-03-05 | — | — | CN | claimed |
| CN-1400973-A | Novel biarylcarboxamides | ASTRAZENECA AB (SE) | 2003-03-05 | — | — | CN | disclosed |