Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.61 |
| ▸ | RAB9A | P51151 | 5/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.56 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.56 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3647399 | 1.00 | NPC1 (0.61) | NPC1RAB9AL3MBTL1TDP1EHMT2 | |
| Hydrogen Sulfide SCHEMBL27801563 | 0.98 | NPC1 (0.59) | NPC1RAB9AL3MBTL1TDP1EHMT2 | |
| SCHEMBL2304581 | 0.85 | NPC1 (0.72) | NPC1RAB9AL3MBTL1TDP1EHMT2 | |
| SCHEMBL2304577 | 0.85 | NPC1 (0.72) | NPC1RAB9AL3MBTL1TDP1EHMT2 | |
| SCHEMBL3510033 | 0.85 | EHMT2 (0.57) | NPC1RAB9AL3MBTL1TDP1EHMT2 | |
| SCHEMBL2391787 | 0.80 | RAB9A (0.61) | NPC1RAB9AL3MBTL1TDP1EHMT2 | |
| SCHEMBL3955037 | 0.77 | — | — | |
| SCHEMBL7205329 | 0.76 | EHMT2 (0.61) | NPC1RAB9AL3MBTL1TDP1EHMT2 | |
| SCHEMBL28462526 | 0.76 | L3MBTL1 (1.00) | NPC1RAB9AL3MBTL1TDP1EHMT2 | |
| SCHEMBL10715337 | 0.76 | L3MBTL1 (1.00) | NPC1RAB9AL3MBTL1TDP1EHMT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8378340-B2 | Aromatic compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-02-19 | — | — | US | disclosed |
| US-20120238765-A1 | AROMATIC COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-09-20 | — | — | US | disclosed |
| US-8222426-B2 | Aromatic compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-07-17 | — | — | US | disclosed |
| US-7842941-B2 | Aromatic compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-11-30 | — | — | US | disclosed |
| US-20100256396-A1 | AROMATIC COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-10-07 | — | — | US | disclosed |
| US-20070063190-A1 | Aromatic compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100256396-A1 | AROMATIC COMPOUND | AHR, AR, NR0B1 | NPC1 1904/4885RAB9A 1837/4885L3MBTL1 1569/4885 |
| US-20070063190-A1 | Aromatic compound | AHR, AR, NR0B1 | NPC1 1826/4885RAB9A 1957/4885L3MBTL1 1394/4885 |
| US-20120238765-A1 | AROMATIC COMPOUND | AHR, AR, NR0B1 | NPC1 1904/4885RAB9A 1837/4885L3MBTL1 1569/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.