Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
| ▸ | TYK2 | P29597 | 1/20 | 0.33 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.31 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.31 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.31 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.31 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.31 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.31 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.31 |
| ▸ | PLAT | P00750 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5780720 | 0.85 | KDM4E (0.37) | KDM4EALDH1A1LMNATSHRBLM | |
| SCHEMBL5777179 | 0.80 | ALDH1A1 (0.48) | KDM4EALDH1A1LMNATSHRBLM | |
| SCHEMBL5777367 | 0.74 | KDM4E (0.48) | KDM4EALDH1A1LMNATSHRBLM | |
| SCHEMBL14845174 | 0.72 | ALDH1A1 (0.49) | KDM4EALDH1A1LMNATSHRBLM | |
| SCHEMBL5776756 | 0.70 | KDM4E (0.34) | KDM4EALDH1A1LMNATSHRBLM | |
| SCHEMBL27572308 | 0.70 | KDM4E (0.39) | KDM4EALDH1A1LMNATYK2HPGD | |
| SCHEMBL5814129 | 0.67 | ADORA2A (0.35) | KDM4EALDH1A1LMNATSHRBLM | |
| SCHEMBL27569468 | 0.64 | TYK2 (0.36) | KDM4EALDH1A1TYK2PLAT | |
| SCHEMBL11221088 | 0.63 | TSHR (0.59) | KDM4EALDH1A1LMNATSHRBLM | |
| SCHEMBL14845123 | 0.62 | LMNA (0.43) | KDM4EALDH1A1LMNATSHRBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1414951-A | Drug discharge pump inhibitor | FUNDAMENTAL THERAPEUTICAL INC (US) | 2003-04-30 | — | — | CN | disclosed |