Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11996374 | 0.75 | SLC6A3 (0.39) | ALDH1A1KDM4EHPGDHSD17B10SLC6A3 | |
| SCHEMBL28550307 | 0.73 | AOC3 (0.42) | ALDH1A1KDM4EHPGDHSD17B10SLC6A3 | |
| SCHEMBL9027058 | 0.71 | AOC3 (0.44) | ALDH1A1KDM4EHPGDHSD17B10SLC6A3 | |
| SCHEMBL3640169 | 0.71 | AOC3 (0.44) | ALDH1A1KDM4EAOC3NPC1RAB9A | |
| SCHEMBL73543 | 0.70 | AOC3 (0.47) | ALDH1A1KDM4EHPGDHSD17B10SLC6A3 | |
| SCHEMBL10441226 | 0.69 | AOC3 (0.42) | ALDH1A1KDM4EAOC3NPC1RAB9A | |
| SCHEMBL11471442 | 0.69 | SMN1; SMN2 (0.46) | SLC6A3SMN1; SMN2CYP2C19 | |
| SCHEMBL7134526 | 0.68 | FLT3 (0.39) | ALDH1A1KDM4EHPGDHSD17B10SLC6A3 | |
| SCHEMBL7029714 | 0.68 | FLT3 (0.39) | ALDH1A1KDM4EHPGDHSD17B10SLC6A3 | |
| SCHEMBL29286331 | 0.68 | FLT3 (0.39) | ALDH1A1KDM4EHPGDHSD17B10SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1336925-A | 4,5,6 and 7-indole and indoline derivatives, their prepn. and use | LUNDBECK & CO AS H (DK) | 2002-02-20 | — | — | CN | disclosed |