Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.39 |
| ▸ | FLT3 | P36888 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA3 | P07451 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9027058 | 0.79 | AOC3 (0.44) | AOC3NPC1RAB9ALOXL2FLT3 | |
| SCHEMBL73543 | 0.75 | AOC3 (0.47) | AOC3NPC1RAB9ALOXL2FLT3 | |
| SCHEMBL9704857 | 0.74 | DRD2 (0.50) | SLC6A3SLC6A4 | |
| SCHEMBL28748112 | 0.73 | ALDH1A1 (0.44) | AOC3NPC1RAB9APOLBSMN1; SMN2 | |
| SCHEMBL7029714 | 0.73 | FLT3 (0.39) | AOC3NPC1RAB9ALOXL2FLT3 | |
| SCHEMBL7134526 | 0.73 | FLT3 (0.39) | AOC3NPC1RAB9ALOXL2FLT3 | |
| SCHEMBL29286331 | 0.73 | FLT3 (0.39) | AOC3NPC1RAB9ALOXL2FLT3 | |
| SCHEMBL3640169 | 0.72 | AOC3 (0.44) | AOC3NPC1RAB9ALOXL2FLT3 | |
| SCHEMBL10441226 | 0.70 | AOC3 (0.42) | AOC3NPC1RAB9ALOXL2FLT3 | |
| SCHEMBL11996374 | 0.70 | SLC6A3 (0.39) | AOC3NPC1RAB9ALOXL2FLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112047871-B | Preparation method of indole compound | 南京大学 | 2022-06-21 | — | — | CN | disclosed |
| CN-112047871-A | Preparation method of indole compound | 南京大学 | 2020-12-08 | — | — | CN | disclosed |