Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 2/20 | 0.39 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.38 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.38 |
| ▸ | DAO | P14920 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.38 |
| ▸ | DDO | Q99489 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7029714 | 1.00 | FLT3 (0.39) | FLT3PTPN2PTPN1SLC6A3SLC6A4 | |
| SCHEMBL7134526 | 1.00 | FLT3 (0.39) | FLT3PTPN2PTPN1SLC6A3SLC6A4 | |
| SCHEMBL29666130 | 0.78 | DAO (0.42) | DAOMAPT | |
| SCHEMBL9027058 | 0.78 | AOC3 (0.44) | FLT3PTPN2PTPN1SLC6A3SLC6A4 | |
| SCHEMBL6007587 | 0.74 | SLC6A3 (0.41) | FLT3SLC6A3SLC6A4AOC3DAO | |
| SCHEMBL28550307 | 0.73 | AOC3 (0.42) | FLT3SLC6A3SLC6A4AOC3DAO | |
| SCHEMBL8362416 | 0.72 | PYGL (0.54) | SLC5A2KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL5823173 | 0.72 | PYGL (0.54) | SLC5A2KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL73543 | 0.70 | AOC3 (0.47) | FLT3SLC6A3SLC6A4AOC3DAO | |
| SCHEMBL28748112 | 0.68 | ALDH1A1 (0.44) | SLC6A3SLC6A4AOC3KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109071435-A | Indoline derivative object includes their compositions and application thereof | 耶路撒冷希伯来大学伊森姆研究发展公司 | 2018-12-21 | — | — | CN | disclosed |