Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | HPGDS | O60760 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | PDE2A | O00408 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29606918 | 1.00 | SLC18A3 (0.46) | SLC18A3HDAC1HDAC6ALDH1A1KMT2A | |
| SCHEMBL19464267 | 0.80 | KDM4E (0.49) | SLC18A3ALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL6964086 | 0.80 | KDM4E (0.49) | SLC18A3ALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL15437887 | 0.79 | KDM4E (0.48) | SLC18A3ALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL15437829 | 0.79 | KDM4E (0.48) | SLC18A3ALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL15437879 | 0.79 | KDM4E (0.48) | SLC18A3ALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL30667867 | 0.75 | MCL1 (0.47) | ALDH1A1KMT2AMEN1 | |
| SCHEMBL8093410 | 0.75 | SLC18A3 (0.58) | SLC18A3HDAC1HDAC6ALDH1A1KMT2A | |
| SCHEMBL24993510 | 0.72 | GRM5 (0.38) | ALDH1A1GRM5KDM4E | |
| SCHEMBL23104457 | 0.72 | GRM5 (0.38) | ALDH1A1GRM5KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114437025-B | Racemization 6-methyl nicotine and preparation method and application thereof | 上海零诺生物科技有限公司 | 2023-08-25 | — | — | CN | claimed |
| CN-114437025-A | Racemic 6-methylnicotine and preparation method and application thereof | 上海零诺生物科技有限公司 | 2022-05-06 | — | — | CN | claimed |
| CN-114437025-B | Racemization 6-methyl nicotine and preparation method and application thereof | 上海零诺生物科技有限公司 | 2023-08-25 | — | — | CN | disclosed |
| CN-114437025-B | Racemization 6-methyl nicotine and preparation method and application thereof | 上海零诺生物科技有限公司 | 2023-08-25 | — | — | CN | disclosed |
| CN-114437025-A | Racemic 6-methylnicotine and preparation method and application thereof | 上海零诺生物科技有限公司 | 2022-05-06 | — | — | CN | disclosed |
| CN-114437025-A | Racemic 6-methylnicotine and preparation method and application thereof | 上海零诺生物科技有限公司 | 2022-05-06 | — | — | CN | disclosed |