Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 3/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9980653 | 0.89 | KMT2A (0.62) | SLC18A3HDAC1HDAC6ALDH1A1LMNA | |
| SCHEMBL10139009 | 0.79 | SLC18A3 (0.58) | SLC18A3ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL9980847 | 0.78 | KMT2A (0.58) | SLC18A3KMT2A | |
| SCHEMBL2428570 | 0.78 | NAPRT (0.58) | ALDH1A1NPC1RAB9A | |
| SCHEMBL22736231 | 0.78 | NPC1 (0.41) | SLC18A3MEN1KMT2ANPC1RAB9A | |
| SCHEMBL13450311 | 0.78 | GABRP (0.58) | SLC18A3HDAC1HDAC6NPC1RAB9A | |
| SCHEMBL4400941 | 0.76 | HDAC1 (0.64) | HDAC1HDAC6ALDH1A1LMNAMEN1 | |
| SCHEMBL28748482 | 0.75 | SLC18A3 (0.46) | SLC18A3HDAC1HDAC6ALDH1A1LMNA | |
| SCHEMBL29606918 | 0.75 | SLC18A3 (0.46) | SLC18A3HDAC1HDAC6ALDH1A1LMNA | |
| SCHEMBL181465 | 0.74 | HDAC1 (0.62) | HDAC1HDAC6ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008130481-A1 | 2-CYANOPHENYL FUSED HETEROCYCLIC COMPOUNDS, AND COMPOSITIONS AND USES THEREOF | RENOVIS, INC. (US) | 2008-10-30 | — | — | WO | disclosed |