Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | NPC1 | O15118 | 5/20 | 0.50 |
| ▸ | RAB9A | P51151 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 9/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | GSK3B | P49841 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.44 |
| ▸ | FEN1 | P39748 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL287873 | 0.75 | ALDH1A1 (0.53) | ALDH1A1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL9048908 | 0.74 | ALDH1A1 (0.56) | ALDH1A1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL9048897 | 0.74 | ALDH1A1 (0.56) | ALDH1A1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL2966649 | 0.73 | ALDH1A1 (0.64) | ALDH1A1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL1232758 | 0.73 | — | — | |
| SCHEMBL758450 | 0.72 | ALDH1A1 (0.62) | ALDH1A1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL9237990 | 0.70 | NPC1 (0.60) | ALDH1A1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL81392 | 0.70 | ALDH1A1 (0.62) | ALDH1A1NPC1RAB9AMEN1KMT2A | |
| Methylamine SCHEMBL29014474 | 0.70 | ALDH1A1 (0.64) | ALDH1A1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL3177576 | 0.70 | LMNA (0.77) | ALDH1A1NPC1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427432-A2 | NOVEL HETEROCYCLIC COMPOUNDS | Torrent Pharmaceuticals Limited (IN) | 2012-03-14 | — | — | EP | disclosed |
| WO-2010128528-A2 | NOVEL HETEROCYCLIC COMPOUNDS | TORRENT PHARMACEUTICALS LIMITED (IN) | 2010-11-11 | — | — | WO | disclosed |