Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.62 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.56 |
| ▸ | FEN1 | P39748 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 6/20 | 0.55 |
| ▸ | NPC1 | O15118 | 5/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | GSK3B | P49841 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.49 |
| ▸ | RELA | Q04206 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2510976 | 0.85 | LMNA (0.68) | ALDH1A1RAB9ANPC1LMNAMEN1 | |
| SCHEMBL1143695 | 0.84 | ERCC5 (0.61) | ALDH1A1ERCC5FEN1RAB9ANPC1 | |
| SCHEMBL1694502 | 0.84 | ERCC5 (0.61) | ALDH1A1ERCC5FEN1RAB9ANPC1 | |
| SCHEMBL11824893 | 0.81 | LMNA (0.64) | ALDH1A1RAB9ANPC1LMNAMEN1 | |
| SCHEMBL3828241 | 0.81 | HPGD (0.63) | ALDH1A1RAB9ANPC1LMNAMEN1 | |
| SCHEMBL3382084 | 0.81 | HPGD (0.63) | ALDH1A1RAB9ANPC1LMNAMEN1 | |
| SCHEMBL28789575 | 0.81 | ALDH1A1 (0.56) | ALDH1A1RAB9ANPC1LMNAMEN1 | |
| SCHEMBL711360 | 0.80 | RAB9A (0.75) | ALDH1A1ERCC5FEN1RAB9ANPC1 | |
| SCHEMBL1222336 | 0.80 | ALDH1A1 (0.61) | ALDH1A1RAB9ANPC1POLBNPSR1 | |
| SCHEMBL10576144 | 0.79 | ALDH1A1 (0.54) | ALDH1A1RAB9ANPC1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 317 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113024540-B | Preparation method and application of nonlinear compound with D-pi-A structure | 中国工程物理研究院激光聚变研究中心 | 2022-03-04 | — | — | CN | claimed |
| CN-113024540-A | Preparation method and application of nonlinear compound with D-pi-A structure | 中国工程物理研究院激光聚变研究中心 | 2021-06-25 | — | — | CN | claimed |
| EP-1405917-B1 | Process for the production of 3-Heteroaryl-3-hydroxy-propionic acid derivatives by enantioselective microbial reduction | SALTIGO GMBH (DE) | 2013-08-14 | — | — | EP | claimed |
| US-8293899-B2 | Ketone transfer hydrogenation of stereoisomerically enriched 3-heteroaryl-3-oxocarboxylic esters by reducing 3-heteroaryl-3-hydroxycarboxylic esters in the presence of a ruthenium-containing catalyst, an amine and formic acid and/or formates | LANXESS DEUTSCHLAND GMBH (DE) | 2012-10-23 | — | — | US | claimed |
| CN-1445224-B | Process for preparing arylaminopropanols | SALTIGO GMBH | 2012-07-11 | — | — | CN | claimed |
| EP-1346977-B1 | Method for producing aryl-aminopropanols | SALTIGO GMBH (DE) | 2009-07-22 | — | — | EP | claimed |
| US-20080262247-A1 | Process for preparing arylaminopropanols | ECKERT MARKUS | 2008-10-23 | — | — | US | claimed |
| EP-1340746-B1 | Process for the reduction of 3-heteroaryl-3-oxo-propanoic acid derivatives | SALTIGO GMBH (DE) | 2007-02-28 | — | — | EP | claimed |
| US-7169938-B2 | Process for preparing arylaminopropanols | LANXESS DEUTSCHLAND GMBH (DE) | 2007-01-30 | — | — | US | claimed |
| CN-1497048-A | Method for preparing 3-heteroarylradical-3-hydroxy-propionic acid derivative | 拜尔公司 | 2004-05-19 | — | — | CN | claimed |
| EP-1405917-A2 | Process for the production of 3-Heteroaryl-3-hydroxy-propionic acid derivatives by enantioselective microbial reduction | Bayer Chemicals AG (DE) | 2004-04-07 | — | — | EP | claimed |
| US-20030225153-A1 | Process for preparing arylaminopropanols | LANXESS DEUTSCHLAND GMBH (DE) | 2003-12-04 | — | — | US | claimed |
| US-20030225274-A1 | Process for reducing 3-heteroaryl-3-oxopropionic acid derivatives | LANXESS DEUTSCHLAND GMBH (DE) | 2003-12-04 | — | — | US | claimed |
| CN-1445224-A | Process for preparing arylaminopropanols | BAYER AG (DE) | 2003-10-01 | — | — | CN | claimed |
| EP-1346977-A1 | Method for producing aryl-aminopropanols | Bayer Aktiengesellschaft (DE) | 2003-09-24 | — | — | EP | claimed |
| EP-1340746-A1 | Process for the reduction of 3-heteroaryl-3-oxo-propanoic acid derivatives | BAYER AG (DE) | 2003-09-03 | — | — | EP | claimed |
| US-12378200-B2 | Oxopyridine derivatives useful as aminocarboxymuconate semialdehyde decarboxylase (ACMSD) inhibitors | ORSOBIO, INC. (US) | 2025-08-05 | — | — | US | disclosed |
| CN-119330931-A | Synthesis method of 2- (benzenesulfonamide) -3-oxo-3-heterocyclic propionate compound | 郑州大学 | 2025-01-21 | — | — | CN | disclosed |
| US-4728647-A | Amides derived from quinoline, and anxiolytic compositions containing them | RHONE-POULENC SANTE (FR) | 1988-03-01 | — | — | US | disclosed |
| US-4035190-A | 2-ISOXAZOLIN-3-HETEROCYCLIC-SUBSTITUTED | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1977-07-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12378200-B2 | Oxopyridine derivatives useful as aminocarboxymuconate semialdehyde decarboxylase (ACMSD) inhibitors | ALDH7A1, ACMSD, AMD1 | ALDH1A1 370/4885ERCC5 1606/4885FEN1 837/4885 |
| US-20030225153-A1 | Process for preparing arylaminopropanols | AHR, CYP1A1, CYP1A2 | ALDH1A1 233/4885ERCC5 2879/4885FEN1 1941/4885 |
| US-20080262247-A1 | Process for preparing arylaminopropanols | CYP1A1, CYP1A2, AHR | ALDH1A1 179/4885ERCC5 2967/4885FEN1 1728/4885 |
| US-20030225274-A1 | Process for reducing 3-heteroaryl-3-oxopropionic acid derivatives | GRHPR, HPD, HAAO | ALDH1A1 273/4885ERCC5 1067/4885FEN1 1305/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.