Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1B | P00325 | 1/20 | 0.41 |
| ▸ | ADH1C | P00326 | 1/20 | 0.41 |
| ▸ | ADH1A | P07327 | 1/20 | 0.41 |
| ▸ | ADH4 | P08319 | 1/20 | 0.41 |
| ▸ | ADH7 | P40394 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.34 |
| ▸ | MLYCD | O95822 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 7/20 | 0.34 |
| ▸ | JAK1 | P23458 | 7/20 | 0.34 |
| ▸ | TYK2 | P29597 | 7/20 | 0.34 |
| ▸ | JAK3 | P52333 | 7/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5394673 | 0.98 | ADH1B (0.40) | ADH1BADH1CADH1AADH4ADH7 | |
| SCHEMBL4120441 | 0.93 | ADH1B (0.45) | ADH1BADH1CADH1AADH4ADH7 | |
| SCHEMBL4117086 | 0.90 | JAK2 (0.38) | JAK2JAK1TYK2JAK3CYP2D6 | |
| Hydrochloric Acid SCHEMBL5390694 | 0.88 | JAK2 (0.37) | JAK2JAK1TYK2JAK3CYP2D6 | |
| SCHEMBL20220242 | 0.82 | ADH1B (0.39) | ADH1BADH1CADH1AADH4ADH7 | |
| SCHEMBL30837752 | 0.80 | CNR2 (0.33) | JAK2JAK1TYK2JAK3CYP2D6 | |
| SCHEMBL16480078 | 0.80 | SAT1 (0.35) | JAK2JAK1TYK2JAK3SAT1 | |
| SCHEMBL28722472 | 0.80 | JAK2 (0.34) | JAK2JAK1TYK2JAK3SAT1 | |
| SCHEMBL28722473 | 0.80 | JAK2 (0.34) | JAK2JAK1TYK2JAK3SAT1 | |
| Hydrochloric Acid SCHEMBL572464 | 0.79 | GNAI3 (0.47) | JAK2JAK1TYK2JAK3EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1499972-A | Imidazolyl derivatives as corticotropin releasing factor inhibitors | ����˹�ж�-����˹˹������˾ | 2004-05-26 | — | — | CN | disclosed |