Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | NAAA | Q02083 | 2/20 | 0.48 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.42 |
| ▸ | STAMBP | O95630 | 1/20 | 0.42 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.42 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | MLYCD | O95822 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28942011 | 0.87 | NAAA (0.53) | SMN1; SMN2NAAALMNAL3MBTL1HDAC11 | |
| SCHEMBL5044578 | 0.85 | SMN1; SMN2 (0.48) | SMN1; SMN2NAAACAMK2DLMNAL3MBTL1 | |
| SCHEMBL1855567 | 0.84 | NAAA (0.46) | SMN1; SMN2NAAACAMK2DLMNACYP1A2 | |
| SCHEMBL27601089 | 0.83 | NAAA (0.62) | SMN1; SMN2NAAAROCK2BCHEACHE | |
| SCHEMBL1855176 | 0.82 | NAAA (0.68) | SMN1; SMN2NAAAROCK2BCHEACHE | |
| SCHEMBL28752185 | 0.82 | SNCA (0.55) | SMN1; SMN2NAAAROCK2BCHEKDM1A | |
| SCHEMBL27601110 | 0.82 | SMN1; SMN2 (0.54) | SMN1; SMN2NAAAROCK2BCHEACHE | |
| SCHEMBL27619615 | 0.81 | NAAA (0.53) | SMN1; SMN2NAAAROCK2BCHEACHE | |
| SCHEMBL27619602 | 0.81 | TRPV1 (0.57) | SMN1; SMN2NAAAHDAC8NPC1RAB9A | |
| SCHEMBL27619583 | 0.80 | SMN1; SMN2 (0.58) | SMN1; SMN2NAAAROCK2KDM1AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100410236-C | Substituted methylene amide derivatives as protein tyrosine phosphatase modulators | APPLIED RESEARCH SYSTEMS (CH) | 2008-08-13 | — | — | CN | disclosed |
| CN-1633410-A | Substituted methylene amide derivatives as protein tyrosine phosphatase modulators | APPLIED RESEARCH SYSTEMS (AN) | 2005-06-29 | — | — | CN | disclosed |