Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 6/20 | 0.47 |
| ▸ | MLYCD | O95822 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | NAMPT | P43490 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | THRA | P10827 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28752186 | 0.87 | SMN1; SMN2 (0.49) | NAAAL3MBTL1HDAC3MLYCDHDAC8 | |
| SCHEMBL27619596 | 0.82 | NAAA (0.74) | NAAAL3MBTL1HDAC3MLYCDHDAC1 | |
| SCHEMBL1855827 | 0.81 | NAAA (0.47) | NAAAL3MBTL1HDAC3MLYCDHDAC1 | |
| SCHEMBL27601019 | 0.80 | HDAC8 (0.64) | NAAAL3MBTL1HDAC3MLYCDHDAC1 | |
| SCHEMBL5044262 | 0.80 | L3MBTL1 (0.62) | NAAAL3MBTL1HDAC3MLYCDHDAC1 | |
| SCHEMBL6718542 | 0.80 | NAAA (0.73) | NAAAL3MBTL1HDAC3MLYCDHDAC1 | |
| SCHEMBL5045782 | 0.79 | HDAC8 (0.62) | NAAAL3MBTL1HDAC3MLYCDHDAC1 | |
| SCHEMBL27601093 | 0.79 | HPGD (0.60) | NAAAL3MBTL1HDAC3HDAC1HDAC2 | |
| SCHEMBL28752188 | 0.77 | TRPV1 (0.69) | NAAAL3MBTL1LMNAALDH1A1MAPT | |
| SCHEMBL27619622 | 0.76 | NPC1 (0.72) | NAAAL3MBTL1HDAC3MLYCDHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100410236-C | Substituted methylene amide derivatives as protein tyrosine phosphatase modulators | APPLIED RESEARCH SYSTEMS (CH) | 2008-08-13 | — | — | CN | disclosed |
| CN-1633410-A | Substituted methylene amide derivatives as protein tyrosine phosphatase modulators | APPLIED RESEARCH SYSTEMS (AN) | 2005-06-29 | — | — | CN | disclosed |