Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | GFER | P55789 | 1/20 | 0.30 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.30 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4990849 | 0.83 | MMP13 (0.40) | POLBMAPTMAPK1ALDH1A1 | |
| SCHEMBL27601154 | 0.77 | MAPK1 (0.36) | PARP1POLBBACE1MAPTMAPK1 | |
| SCHEMBL4990294 | 0.75 | POLB (0.43) | POLBMAPTMAPK1ALDH1A1GAA | |
| SCHEMBL6915874 | 0.72 | MAPK1 (0.48) | POLBMAPTMAPK1ALDH1A1GAA | |
| SCHEMBL27809841 | 0.72 | KDM4E (0.47) | PARP1POLBMAPTALDH1A1GAA | |
| SCHEMBL27407292 | 0.71 | CYP4F2 (0.54) | BACE1ALDH1A1GAACYP4F2CYP4A11 | |
| SCHEMBL28766987 | 0.70 | DPP4 (0.42) | MAPTMAOBCYP4F2CYP4A11 | |
| SCHEMBL27583675 | 0.70 | PARP1 (0.40) | PARP1BACE1MAOAMAOBCYP4F2 | |
| SCHEMBL4992838 | 0.70 | SLC7A5 (0.36) | MAPTMAPK1MAOBALDH1A1 | |
| SCHEMBL4992898 | 0.69 | MAPT (0.38) | MAPTMAPK1CYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1476429-A | EP4 receptor selective agonists in treatment of osteoporosis | �Ʒ� | 2004-02-18 | — | — | CN | disclosed |