Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.42 |
| ▸ | PAM | P19021 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | CETP | P11597 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4990294 | 0.87 | POLB (0.43) | MAPK1MAPTGAAPOLBTSHR | |
| SCHEMBL2208952 | 0.85 | CETP (0.48) | MAPK1GAAPOLBTSHRL3MBTL1 | |
| SCHEMBL758293 | 0.83 | TSHR (0.47) | MAPK1MAPTPOLBTSHRL3MBTL1 | |
| SCHEMBL4992838 | 0.81 | SLC7A5 (0.36) | MAPK1MAPTALDH1A1CETPSMN1; SMN2 | |
| SCHEMBL5849992 | 0.81 | ALDH1A1 (0.53) | MAPK1MAPTPOLBTSHRL3MBTL1 | |
| SCHEMBL4992898 | 0.80 | MAPT (0.38) | MAPK1MAPT | |
| SCHEMBL11307576 | 0.79 | TSHR (0.51) | MAPK1MAPTPOLBTSHRALDH1A1 | |
| SCHEMBL16601102 | 0.78 | ALOX15 (0.49) | MAPK1MAPTPOLBTSHRSMN1; SMN2 | |
| SCHEMBL13142812 | 0.77 | NR1I2 (0.54) | MAPK1MAPTGAAPOLBTSHR | |
| Hydrogen Peroxide SCHEMBL8609887 | 0.77 | NPY5R (0.49) | MAPK1MAPTPOLBTSHRNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004026245-A2 | SUBSTITUTED PHOSPHONATE COMPOUNDS HAVING BONE ANABOLIC ACTIVITY | ILEX ONCOLOGY RESEARCH, SARL (CH) | 2004-04-01 | — | — | WO | disclosed |
| EP-0638084-A1 | SUBSTITUTED PHOSPHONATES, THE PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SYMPHAR S.A. (CH) | 1995-02-15 | — | — | EP | disclosed |
| WO-1994019358-A1 | SUBSTITUTED PHOSPHONATES, THE PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SYMPHAR S.A. (CH) | 1994-09-01 | — | — | WO | disclosed |