Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4998782 | 0.84 | MAPK1 (0.38) | MAPK1MAPTHPGDALOX15TSHR | |
| SCHEMBL28752198 | 0.77 | PARP1 (0.33) | MAPK1MAPTPARP1POLBBACE1 | |
| SCHEMBL13725745 | 0.67 | GABRR1 (0.52) | MAPK1MAPTTSHRPOLB | |
| SCHEMBL5071677 | 0.67 | THRA (0.37) | MAPK1MAPT | |
| SCHEMBL15317935 | 0.67 | TSHR (0.48) | MAPK1MAPTHPGDALOX15TSHR | |
| SCHEMBL15032899 | 0.66 | TSHR (0.52) | MAPK1MAPTTSHRPOLB | |
| SCHEMBL27703412 | 0.65 | POLB (0.38) | MAPTCYP2C19TSHRNPSR1POLB | |
| SCHEMBL27407292 | 0.65 | CYP4F2 (0.54) | BACE1ALDH1A1 | |
| SCHEMBL27663597 | 0.65 | LOXL2 (0.48) | PARP1 | |
| SCHEMBL16825119 | 0.64 | ALDH1A1 (0.38) | MAPTHPGDTSHRPOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1476429-A | EP4 receptor selective agonists in treatment of osteoporosis | �Ʒ� | 2004-02-18 | — | — | CN | disclosed |