Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL287235 | 0.79 | TSHR (0.63) | TSHRALDH1A1KMT2AMEN1RAB9A | |
| SCHEMBL287525 | 0.73 | ALDH1A1 (0.50) | TSHRALDH1A1RAB9ANPSR1TDP1 | |
| SCHEMBL9767800 | 0.68 | ALDH1A1 (0.67) | TSHRALDH1A1KMT2AMEN1RAB9A | |
| SCHEMBL2860044 | 0.66 | KDM4E (0.68) | TSHRALDH1A1KMT2AMEN1NPSR1 | |
| SCHEMBL10501732 | 0.66 | KDM4E (0.78) | TSHRALDH1A1KMT2ANPSR1TP53 | |
| SCHEMBL7312805 | 0.66 | LMNA (0.71) | TSHRALDH1A1NPSR1TP53TDP1 | |
| SCHEMBL31126834 | 0.66 | KDM4E (0.68) | TSHRALDH1A1KMT2AMEN1NPSR1 | |
| SCHEMBL10438008 | 0.66 | KDM4E (0.68) | TSHRALDH1A1RAB9ANPSR1TP53 | |
| SCHEMBL422787 | 0.65 | RAB9A (0.62) | TSHRALDH1A1KMT2AMEN1RAB9A | |
| SCHEMBL14085807 | 0.65 | KDM4E (0.76) | TSHRALDH1A1KMT2ANPSR1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427432-A2 | NOVEL HETEROCYCLIC COMPOUNDS | Torrent Pharmaceuticals Limited (IN) | 2012-03-14 | — | — | EP | disclosed |
| WO-2010128528-A2 | NOVEL HETEROCYCLIC COMPOUNDS | TORRENT PHARMACEUTICALS LIMITED (IN) | 2010-11-11 | — | — | WO | disclosed |