Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 9/20 | 0.54 |
| ▸ | MMP2 | P08253 | 9/20 | 0.54 |
| ▸ | MMP13 | P45452 | 8/20 | 0.54 |
| ▸ | MMP3 | P08254 | 7/20 | 0.54 |
| ▸ | MMP1 | P03956 | 6/20 | 0.54 |
| ▸ | MMP7 | P09237 | 6/20 | 0.54 |
| ▸ | ADAMTS4 | O75173 | 5/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.41 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.41 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.41 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3612014 | 1.00 | MMP9 (0.54) | MMP9MMP2MMP13MMP3MMP1 | |
| SCHEMBL3607260 | 0.90 | MMP9 (0.58) | MMP9MMP2MMP13MMP3MMP1 | |
| SCHEMBL3620408 | 0.85 | MMP9 (0.47) | MMP9MMP2MMP13MMP3MMP1 | |
| SCHEMBL1655654 | 0.76 | ADAMTS4 (0.67) | MMP9MMP2MMP13MMP3MMP1 | |
| SCHEMBL8283343 | 0.76 | ADAMTS4 (0.67) | MMP9MMP2MMP13MMP3MMP1 | |
| SCHEMBL3103313 | 0.76 | MMP2 (0.77) | MMP9MMP2MMP13MMP3MMP1 | |
| SCHEMBL7935790 | 0.76 | MMP2 (0.69) | MMP9MMP2MMP13MMP3MMP1 | |
| SCHEMBL3617858 | 0.76 | MMP2 (0.77) | MMP9MMP2MMP13MMP3MMP1 | |
| SCHEMBL13978774 | 0.76 | MMP2 (0.52) | MMP9MMP2MMP13MMP3MMP1 | |
| SCHEMBL3608270 | 0.75 | MMP2 (0.68) | MMP9MMP2MMP13MMP3MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1623537-A | Biaryl sulfonamides and its using method | WYETH CORP (US) | 2005-06-08 | — | — | CN | disclosed |