Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 3/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.45 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.45 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.44 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.44 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.44 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.44 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.43 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.43 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.43 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.43 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.43 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29674787 | 0.83 | AKR1B1 (0.61) | AKR1B1TDP1PTGS2KDM4ECYP1A2 | |
| SCHEMBL286410 | 0.83 | AKR1B1 (0.61) | AKR1B1TDP1PTGS2KDM4ECYP1A2 | |
| SCHEMBL30565097 | 0.83 | AKR1B1 (0.61) | AKR1B1TDP1PTGS2KDM4ECYP1A2 | |
| SCHEMBL29049638 | 0.82 | GABRA1 (0.45) | MAPTGABRA1GABRB2 | |
| SCHEMBL14530966 | 0.82 | AKR1B1 (0.67) | AKR1B1TDP1PTGS2ABCB11PTGS1 | |
| SCHEMBL11028284 | 0.82 | GABRA1 (0.40) | TDP1GABRA1GABRB2 | |
| SCHEMBL28784843 | 0.82 | AKR1B1 (0.50) | AKR1B1TDP1PTGS2ABCB11PTGS1 | |
| SCHEMBL2730028 | 0.82 | AKR1B1 (0.55) | AKR1B1TDP1PTGS2ABCB11PTGS1 | |
| SCHEMBL1364609 | 0.82 | GABRA1 (0.68) | AKR1B1TDP1PTGS2ABCB11PTGS1 | |
| Hydrochloric Acid SCHEMBL2532034 | 0.81 | AKR1B1 (0.59) | AKR1B1TDP1PTGS2KDM4ECYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1490322-B1 | METHOD FOR PRODUCING 2,2-DICHLORO OR DIBROMO-PHENYL ALKYL ACETATES | DSM FINE CHEM AUSTRIA GMBH (AT) | 2015-07-29 | — | — | EP | claimed |
| US-20050131246-A1 | Method for producing 2,2-dichloro or dibromo-phenyl alkyl acetates | DSM FINE CHEMICALS AUSTRIA NFG GMBH & CO KG (AT) | 2005-06-16 | — | — | US | claimed |
| EP-0975583-B1 | AROMATIC AMIDES, THEIR PREPARATION PROCESS AND THEIR USE AS PESTICIDES | MERIAL LTD (US) | 2010-10-20 | — | — | EP | disclosed |
| US-20050131246-A1 | Method for producing 2,2-dichloro or dibromo-phenyl alkyl acetates | DSM FINE CHEMICALS AUSTRIA NFG GMBH & CO KG (AT) | 2005-06-16 | — | — | US | disclosed |
| US-6555709-B1 | Derivatives of 4-(naphth-2-ylmethyl)-N-(2-methylphenyl) benzamide; storing crops (cotton and rice); insecticides; miticides; nematocides; molluscs; anthelmintics; acarina; textiles; foods | HOECHST SCHERING AGREVO S.A. (FR) | 2003-04-29 | — | — | US | disclosed |
| EP-0975583-A1 | AROMATIC AMIDES, THEIR PREPARATION PROCESS AND THEIR USE AS PESTICIDES | Hoechst Schering AgrEvo S.A. (FR) | 2000-02-02 | — | — | EP | disclosed |
| WO-1998045252-A1 | AROMATIC AMIDES, THEIR PREPARATION PROCESS AND THEIR USE AS PESTICIDES | HOECHST SCHERING AGREVO S.A. (FR) | 1998-10-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050131246-A1 | Method for producing 2,2-dichloro or dibromo-phenyl alkyl acetates | CBR1, CBR3, ADH1C | AKR1B1 17/4885TDP1 2540/4885PTGS2 2424/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.