Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA2 | P47869 | 5/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 5/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.30 |
| ▸ | CDK1 | P06493 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3230517 | 0.86 | GABRA2 (0.33) | GABRA2GABRB2KDM4EKMT2A | |
| SCHEMBL3221011 | 0.84 | — | — | |
| Iodosulfuron SCHEMBL2881870 | 0.82 | CDK1 (0.33) | CDK1 | |
| Iodosulfuron SCHEMBL3262629 | 0.82 | — | — | |
| SCHEMBL3230430 | 0.79 | CDK1 (0.36) | GABRA2GABRB2ALDH1A1KDM4ENPC1 | |
| SCHEMBL2372927 | 0.78 | — | — | |
| Iodosulfuron SCHEMBL119814 | 0.77 | CDK1 (0.42) | ALDH1A1KDM4ENPC1SMN1; SMN2MAPT | |
| Iodosulfuron SCHEMBL7638003 | 0.77 | CDK1 (0.42) | ALDH1A1KDM4ENPC1SMN1; SMN2MAPT | |
| Iodosulfuron SCHEMBL29355338 | 0.77 | CDK1 (0.42) | ALDH1A1KDM4ENPC1SMN1; SMN2MAPT | |
| Iodosulfuron SCHEMBL29686924 | 0.77 | CDK1 (0.42) | ALDH1A1KDM4ENPC1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100150842-A1 | Method and Kit for Detecting Resistance in Living Organisms | AARHUS UNIVERSITET (DK) | 2010-06-17 | — | — | US | disclosed |
| US-20100047176-A1 | Method and Kit for Testing Stress Effects in Living Organisms | AARHUS UNIVERSITET (DK) | 2010-02-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100047176-A1 | Method and Kit for Testing Stress Effects in Living Organisms | DDT, ACHE, WEE1 | GABRA2 4442/4885GABRB2 4700/4885ALDH1A1 574/4885 |
| US-20100150842-A1 | Method and Kit for Detecting Resistance in Living Organisms | DDT, NOTUM, ACHE | GABRA2 4456/4885GABRB2 4720/4885ALDH1A1 618/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.