Iodosulfuron

Iodosulfuron

SCHEMBL2881870

CC1(C(=O)O)CC(C(=O)O)=NN1c1ccc(Cl)cc1Cl.CCCC.COc1cc(OC)nc(NC(=O)NS(=O)(=O)c2cc(CNS(C)(=O)=O)ccc2C(=O)O)n1.COc1nc(C)nc(NC(=O)NS(=O)(=O)c2cc(I)ccc2C(=O)O)n1

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CDK1 P06493 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2373831 0.92 CDK1 (0.38) CDK1
SCHEMBL14655338 0.88 CDK1 (0.38) CDK1
SCHEMBL3221011 0.85
Iodosulfuron SCHEMBL17747148 0.84 CDK1 (0.42) CDK1
Iodosulfuron SCHEMBL2875382 0.82 GABRA2 (0.33) CDK1
SCHEMBL3230430 0.81 CDK1 (0.36) CDK1
SCHEMBL19463615 0.77 CDK1 (0.43) CDK1
SCHEMBL2372927 0.76
SCHEMBL3261513 0.76
SCHEMBL915255 0.75 CDK1 (0.38) CDK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100150842-A1 Method and Kit for Detecting Resistance in Living Organisms AARHUS UNIVERSITET (DK) 2010-06-17 US disclosed
US-20100047176-A1 Method and Kit for Testing Stress Effects in Living Organisms AARHUS UNIVERSITET (DK) 2010-02-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100047176-A1 Method and Kit for Testing Stress Effects in Living Organisms DDT, ACHE, WEE1 CDK1 587/4885
US-20100150842-A1 Method and Kit for Detecting Resistance in Living Organisms DDT, NOTUM, ACHE CDK1 1244/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.