SCHEMBL2875400

SCHEMBL2875400

OCc1cc(OCCCCn2c3ccccc3c3ccccc32)c(OCCCCn2c3ccccc3c3ccccc32)c(OCCCCn2c3ccccc3c3ccccc32)c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PSEN1 P49768 5/20 0.53
PSEN2 P49810 5/20 0.53
APH1B Q8WW43 5/20 0.53
NCSTN Q92542 5/20 0.53
APH1A Q96BI3 5/20 0.53
PSENEN Q9NZ42 5/20 0.53
FABP4 P15090 2/20 0.44
FABP5 Q01469 2/20 0.44
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.42
HDAC1 Q13547 3/20 0.42
HDAC6 Q9UBN7 3/20 0.42
SMPD1 P17405 1/20 0.41
MAOA P21397 5/20 0.40
MAOB P27338 5/20 0.40
ACHE P22303 1/20 0.40
GRIN1 Q05586 1/20 0.40
GRIN2A Q12879 1/20 0.40
GRIN2B Q13224 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2872681 0.91 PSEN1 (0.46) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL13696968 0.83 PSEN1 (0.49) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL13377927 0.79 PSEN1 (0.42) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL13383507 0.79 PSEN1 (0.37) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL2875809 0.79 SCARB1 (0.49) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL14864333 0.77 PSEN1 (0.44) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL2872778 0.76 PSEN1 (0.43) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL4552481 0.72 FABP4 (0.68) FABP4FABP5HDAC1HDAC6MAOA
SCHEMBL2873004 0.70 FABP4 (0.62) FABP4FABP5MEN1KMT2AHDAC1
SCHEMBL3943747 0.70 CNR2 (0.51) PSEN1PSEN2APH1BNCSTNAPH1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8420231-B2 Iridium phosphorescent dendrimer, method of preparing the same and electroluminescent device including the iridium phosphorescent dendrimer SAMSUNG ELECTRONICS CO., LTD. (KR) 2013-04-16 US disclosed
US-8420231-B2 Iridium phosphorescent dendrimer, method of preparing the same and electroluminescent device including the iridium phosphorescent dendrimer SAMSUNG ELECTRONICS CO., LTD. (KR) 2013-04-16 US disclosed
US-8420231-B2 Iridium phosphorescent dendrimer, method of preparing the same and electroluminescent device including the iridium phosphorescent dendrimer SAMSUNG ELECTRONICS CO., LTD. (KR) 2013-04-16 US disclosed
US-20100084970-A1 IRIDIUM PHOSPHORESCENT DENDRIMER, METHOD OF PREPARING THE SAME AND ELECTROLUMINESCENT DEVICE INCLUDING THE IRIDIUM PHOSPHORESCENT DENDRIMER SAMSUNG ELECTRONICS CO., LTD (KR) 2010-04-08 US disclosed
US-20100084970-A1 IRIDIUM PHOSPHORESCENT DENDRIMER, METHOD OF PREPARING THE SAME AND ELECTROLUMINESCENT DEVICE INCLUDING THE IRIDIUM PHOSPHORESCENT DENDRIMER SAMSUNG ELECTRONICS CO., LTD (KR) 2010-04-08 US disclosed
US-20100084970-A1 IRIDIUM PHOSPHORESCENT DENDRIMER, METHOD OF PREPARING THE SAME AND ELECTROLUMINESCENT DEVICE INCLUDING THE IRIDIUM PHOSPHORESCENT DENDRIMER SAMSUNG ELECTRONICS CO., LTD (KR) 2010-04-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100084970-A1 IRIDIUM PHOSPHORESCENT DENDRIMER, METHOD OF PREPARING THE SAME AND ELECTROLUMINESCENT DEVICE INCLUDING THE IRIDIUM PHOSPHORESCENT DENDRIMER DNM1, FIS1, DCUN1D1 PSEN1 3218/4885PSEN2 4384/4885APH1B 3197/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.