Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 1/20 | 0.52 |
| ▸ | MAOA | P21397 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13508978 | 0.80 | HTR7 (0.67) | HTR7MAOAMAOBCA1CA2 | |
| SCHEMBL9296265 | 0.76 | HTR7 (0.52) | HTR7MAOAMAOBCA1CA2 | |
| SCHEMBL31378718 | 0.76 | HTR7 (0.52) | HTR7MAOAMAOBCA1CA2 | |
| SCHEMBL14460773 | 0.76 | HTR7 (0.62) | HTR7MAOAMAOBCA1CA2 | |
| SCHEMBL1802193 | 0.76 | HTR7 (0.57) | HTR7MAOAMAOBCA1CA2 | |
| SCHEMBL23269520 | 0.76 | MAOA (0.61) | HTR7MAOAMAOBCA1CA2 | |
| SCHEMBL30421706 | 0.74 | CYP1A2 (0.61) | HTR7MAOAMAOBALDH1A1RAB9A | |
| SCHEMBL7284578 | 0.73 | MEN1 (0.58) | LMNAAPOBEC3GALDH1A1MAPK1RAB9A | |
| SCHEMBL17195662 | 0.73 | HTR7 (0.63) | HTR7MAOAMAOBCA1CA2 | |
| SCHEMBL4334230 | 0.73 | POLB (0.61) | HTR7MAOAMAOBCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100334092-C | Process for producing cyclic thioether and synthetic intermediate thereof | SANKYO CO (JP) | 2007-08-29 | — | — | CN | disclosed |
| CN-1675221-A | Process for producing cyclic thioether and synthetic intermediate thereof | SANKYO CO (JP) | 2005-09-28 | — | — | CN | disclosed |