SCHEMBL28754249

SCHEMBL28754249

CC(C)(CCF)Cc1ccccc1Br

nearest known ligand 0.44

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 3/20 0.44
IDO1 P14902 2/20 0.38
RIPK1 Q13546 1/20 0.38
TSHR P16473 2/20 0.37
NR3C1 P04150 1/20 0.36
PYCR1 P32322 1/20 0.35
CYP1A2 P05177 1/20 0.34
CYP2D6 P10635 1/20 0.34
NFKB1 P19838 1/20 0.34
CYP2C19 P33261 1/20 0.34
HSD17B10 Q99714 1/20 0.34
SLC6A2 P23975 1/20 0.34
LMNA P02545 2/20 0.33
BLM P54132 1/20 0.33
PLA2G1B P04054 1/20 0.33
ATG4B Q9Y4P1 1/20 0.33
CYP2A13 Q16696 1/20 0.33
ALDH1A1 P00352 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31117942 0.82 TAAR1 (0.50) TAAR1IDO1RIPK1TSHRNR3C1
SCHEMBL11970972 0.80 RIPK1 (0.47) TAAR1IDO1RIPK1TSHRNR3C1
SCHEMBL1691374 0.77 RIPK1 (0.47) TAAR1IDO1RIPK1TSHRNR3C1
SCHEMBL4656444 0.75 TAAR1 (0.39) TAAR1IDO1TSHRPYCR1CYP1A2
SCHEMBL30388724 0.74 RIPK1 (0.45) TAAR1IDO1RIPK1TSHRNR3C1
SCHEMBL15638695 0.74 TAAR1 (0.50) TAAR1IDO1RIPK1TSHRNR3C1
SCHEMBL18623577 0.74 TAAR1 (0.44) TAAR1IDO1RIPK1TSHRNR3C1
SCHEMBL2401345 0.74 RIPK1 (0.45) TAAR1IDO1RIPK1TSHRNR3C1
SCHEMBL263115 0.73 TAAR1 (0.46) TAAR1IDO1RIPK1TSHRNR3C1
Hydrochloric Acid SCHEMBL12802349 0.72 IDO1 (0.48) TAAR1IDO1RIPK1TSHRNR3C1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100584823-C Malononitrile compounds and their use as pesticides SUMITOMO CHEMICAL CO 2010-01-27 CN disclosed
CN-100376549-C Malononitrile compounds and their use as pesticides SUMITOMO CHEMICAL CO (JP) 2008-03-26 CN disclosed
CN-101033200-A Malononitrile compounds and their use as pesticides SUMITOMO CHEMICAL CO (JP) 2007-09-12 CN disclosed
CN-1639114-A Malononitrile compounds and their use as pesticides SUMITOMO CHEMICAL CO (JP) 2005-07-13 CN disclosed