Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.45 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.39 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PDE5A | O76074 | 3/20 | 0.39 |
| ▸ | PDE1A | P54750 | 1/20 | 0.39 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.39 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.38 |
| ▸ | PDE4A | P27815 | 2/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2242864 | 0.76 | MCHR1 (0.51) | MRGPRX1CARM1PRMT1MCHR1PDE5A | |
| SCHEMBL10777264 | 0.76 | MRGPRX1 (0.56) | TSHRMRGPRX1SMN1; SMN2PDE5APDE1A | |
| SCHEMBL28333036 | 0.76 | MRGPRX1 (0.46) | TSHRMRGPRX1CARM1PRMT1MCHR1 | |
| SCHEMBL8105869 | 0.76 | ADRA1A (0.51) | TSHRMRGPRX1SMN1; SMN2PDE5AHPGD | |
| SCHEMBL8523784 | 0.75 | PTGS1 (0.61) | TSHRMRGPRX1CARM1PRMT1SMN1; SMN2 | |
| SCHEMBL9501563 | 0.75 | MRGPRX1 (0.49) | TSHRMRGPRX1SMN1; SMN2PDE4DMAPT | |
| SCHEMBL11779563 | 0.75 | SRC (0.49) | CARM1PRMT1MCHR1SMN1; SMN2HPGD | |
| SCHEMBL5344402 | 0.74 | MCHR1 (0.49) | MRGPRX1CARM1PRMT1MCHR1PDE5A | |
| SCHEMBL8115364 | 0.74 | ADRA1A (0.52) | TSHRMRGPRX1PDE5AHPGDKDM4E | |
| SCHEMBL10848411 | 0.74 | TSHR (0.43) | TSHRMRGPRX1PDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108409684-B | N- (2-cyclohexyloxyphenyl) amide compound and preparation method and application thereof | 上海晓明检测技术服务有限公司 | 2022-04-12 | — | — | CN | claimed |
| CN-108409684-B | N- (2-cyclohexyloxyphenyl) amide compound and preparation method and application thereof | 上海晓明检测技术服务有限公司 | 2022-04-12 | — | — | CN | disclosed |
| CN-108409684-B | N- (2-cyclohexyloxyphenyl) amide compound and preparation method and application thereof | 上海晓明检测技术服务有限公司 | 2022-04-12 | — | — | CN | disclosed |
| CN-108409684-B | N- (2-cyclohexyloxyphenyl) amide compound and preparation method and application thereof | 上海晓明检测技术服务有限公司 | 2022-04-12 | — | — | CN | disclosed |