Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1532583 | 0.80 | TLR2 (0.44) | SMN1; SMN2ALDH1A1MEN1NPC1POLB | |
| SCHEMBL1172092 | 0.80 | TLR2 (0.44) | SMN1; SMN2ALDH1A1MEN1NPC1POLB | |
| SCHEMBL28604790 | 0.80 | LMNA (0.48) | LMNASMN1; SMN2ALDH1A1MEN1NPC1 | |
| SCHEMBL2222143 | 0.78 | KDM4E (0.48) | LMNAHSD17B10GAAALDH1A1MEN1 | |
| Acetic Acid SCHEMBL28235752 | 0.77 | TLR2 (0.43) | SMN1; SMN2ALDH1A1MEN1NPC1POLB | |
| SCHEMBL1892710 | 0.77 | SMN1; SMN2 (0.40) | LMNAHSD17B10CES2CES1SMN1; SMN2 | |
| SCHEMBL28657375 | 0.76 | GABBR2 (0.50) | SMN1; SMN2ALDH1A1MEN1NPC1POLB | |
| SCHEMBL29149060 | 0.75 | CYP1A2 (0.48) | LMNAHSD17B10ALDH1A1POLBCYP1A2 | |
| SCHEMBL27769332 | 0.75 | LMNA (0.43) | LMNAHSD17B10GAASMN1; SMN2MEN1 | |
| SCHEMBL406383 | 0.75 | CYP2D6 (0.47) | SMN1; SMN2ALDH1A1MEN1NPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1610659-A | Carboxylic acid derivatives | TAISHO PHARMACEUTICAL CO LTD (JP) | 2005-04-27 | — | — | CN | disclosed |