Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.53 |
| ▸ | MCHR1 | Q99705 | 15/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.50 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.43 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1003757 | 0.88 | MCHR1 (0.55) | MCHR1KCNH2HRH3 | |
| SCHEMBL21668749 | 0.84 | LIPG (0.49) | GPR119DDB1CRBN | |
| SCHEMBL23839391 | 0.84 | LIPG (0.49) | GPR119DDB1CRBN | |
| SCHEMBL13590834 | 0.78 | GPR119 (0.52) | GPR119DDB1CRBN | |
| SCHEMBL27399047 | 0.77 | GPR119 (0.50) | GPR119DDB1CRBN | |
| SCHEMBL16434872 | 0.76 | BACE1 (0.49) | GPR119DDB1CRBN | |
| SCHEMBL8648747 | 0.75 | ALDH1A1 (0.55) | GPR119 | |
| SCHEMBL7115964 | 0.75 | GPR119 (0.57) | GPR119 | |
| SCHEMBL1005757 | 0.75 | MCHR1 (0.68) | MCHR1 | |
| SCHEMBL2887106 | 0.75 | GPR119 (0.53) | GPR119MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1921065-B1 | PHENYLPYRIDONE DERIVATIVE | BANYU PHARMA CO LTD (JP) | 2010-10-20 | — | — | EP | disclosed |
| EP-1921065-A1 | PHENYLPYRIDONE DERIVATIVE | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2008-05-14 | — | — | EP | disclosed |