Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | MCHR1 | Q99705 | 5/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | LDHA | P00338 | 1/20 | 0.42 |
| ▸ | LDHB | P07195 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.41 |
| ▸ | FPR2 | P25090 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29671970 | 1.00 | LMNA (0.52) | LMNATSHRMCHR1HTR2BTRPA1 | |
| SCHEMBL28755175 | 0.92 | LMNA (0.51) | LMNATSHRMCHR1TRPA1MAPT | |
| SCHEMBL29671962 | 0.92 | LMNA (0.51) | LMNATSHRMCHR1TRPA1MAPT | |
| SCHEMBL29672019 | 0.91 | MAPT (0.50) | LMNATSHRMCHR1TRPA1MAPT | |
| SCHEMBL28755228 | 0.91 | MAPT (0.50) | LMNATSHRMCHR1TRPA1MAPT | |
| SCHEMBL28755158 | 0.90 | MEN1 (0.47) | LMNATSHRMCHR1MAPTSMN1; SMN2 | |
| SCHEMBL29671963 | 0.90 | MEN1 (0.47) | LMNATSHRMCHR1MAPTSMN1; SMN2 | |
| SCHEMBL28755302 | 0.89 | MCHR1 (0.50) | LMNATSHRMCHR1HTR2BTRPA1 | |
| SCHEMBL29671896 | 0.89 | MCHR1 (0.50) | LMNATSHRMCHR1HTR2BTRPA1 | |
| SCHEMBL28755369 | 0.89 | MAPT (0.45) | TSHRMCHR1HTR2BMAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114573582-B | 1,2,3, 4-tetrahydropyrido [2,3-d ] pyrimidine compound and preparation method and application thereof | 沈阳药科大学 | 2023-06-16 | — | — | CN | claimed |
| CN-114573582-A | 1,2,3, 4-tetrahydropyrido [2,3-d ] pyrimidine compound and preparation method and application thereof | 沈阳药科大学 | 2022-06-03 | — | — | CN | claimed |
| CN-114573582-B | 1,2,3, 4-tetrahydropyrido [2,3-d ] pyrimidine compound and preparation method and application thereof | 沈阳药科大学 | 2023-06-16 | — | — | CN | disclosed |
| CN-114573582-A | 1,2,3, 4-tetrahydropyrido [2,3-d ] pyrimidine compound and preparation method and application thereof | 沈阳药科大学 | 2022-06-03 | — | — | CN | disclosed |