Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.47 |
| ▸ | HSD17B13 | Q7Z5P4 | 1/20 | 0.44 |
| ▸ | ACLY | P53396 | 1/20 | 0.42 |
| ▸ | ALPL | P05186 | 2/20 | 0.41 |
| ▸ | SLC22A12 | Q96S37 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | CCR1 | P32246 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.38 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2877986 | 0.85 | CA12 (0.54) | MGAMMAPTSMN1; SMN2CA12CA1 | |
| SCHEMBL2872499 | 0.79 | MGAM (0.46) | MGAMHSD17B13SLC22A12MAPTCCR1 | |
| SCHEMBL2875837 | 0.76 | LMNA (0.55) | SMN1; SMN2GAA | |
| SCHEMBL21550432 | 0.76 | TAAR1 (0.50) | SMN1; SMN2CA12CA1CA2CA5A | |
| SCHEMBL2872987 | 0.75 | NR1H2 (0.57) | — | |
| SCHEMBL2873488 | 0.75 | MGAM (0.47) | MGAMHSD17B13MAPT | |
| SCHEMBL2878392 | 0.74 | MGAM (0.45) | MGAMHSD17B13MAPT | |
| Tert-Butyl Formate SCHEMBL27751384 | 0.74 | MGAM (0.42) | MGAMHSD17B13SLC22A12MAPTCA12 | |
| SCHEMBL2878432 | 0.74 | MGAM (0.45) | MGAMHSD17B13MAPT | |
| Tert-Butyl Formate SCHEMBL27751385 | 0.73 | MGAM (0.39) | MGAMHSD17B13ACLYSLC22A12MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210171456-A1 | NOVEL SULFONAMIDE DERIVATIVES HAVING SELECTIVE NOX INHIBITING ACTIVITY | GLUCOX BIOTECH AB (SE) | 2021-06-10 | — | — | US | claimed |
| US-20250136545-A1 | NOVEL SULFONAMIDE DERIVATIVES HAVING SELECTIVE NOX INHIBITING ACTIVITY | GLUCOX BIOTECH AB (SE) | 2025-05-01 | — | — | US | disclosed |
| US-12202790-B2 | Sulfonamide derivatives having selective Nox inhibiting activity | GLUCOX BIOTECH AB (SE) | 2025-01-21 | — | — | US | disclosed |
| US-20210171456-A1 | NOVEL SULFONAMIDE DERIVATIVES HAVING SELECTIVE NOX INHIBITING ACTIVITY | GLUCOX BIOTECH AB (SE) | 2021-06-10 | — | — | US | disclosed |
| EP-2066628-B1 | 2-PHENYL-INDOLES AS PROSTAGLANDIN D2 RECEPTOR ANTAGONISTS | SANOFI AVENTIS (FR) | 2010-10-20 | — | — | EP | disclosed |
| US-20090176804-A1 | 2-PHENYL-INDOLES AS PROSTAGLANDIN D2 RECEPTOR ANTAGONISTS | SANOFI-AVENTIS (FR) | 2009-07-09 | — | — | US | disclosed |
| EP-2066628-A1 | 2-PHENYL-INDOLES AS PROSTAGLANDIN D2 RECEPTOR ANTAGONISTS | Sanofi-Aventis (FR) | 2009-06-10 | — | — | EP | disclosed |
| WO-2008014186-A1 | 2-PHENYL-INDOLES AS PROSTAGLANDIN D2 RECEPTOR ANTAGONISTS | SANOFI-AVENTIS (FR) | 2008-01-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12202790-B2 | Sulfonamide derivatives having selective Nox inhibiting activity | NOX4, NOX1, NOX5 | MGAM 1807/4885HSD17B13 1591/4885ACLY 2328/4885 |
| US-20210171456-A1 | NOVEL SULFONAMIDE DERIVATIVES HAVING SELECTIVE NOX INHIBITING ACTIVITY | NOX4, NOX1, NOX5 | MGAM 1703/4885HSD17B13 1827/4885ACLY 2249/4885 |
| US-20250136545-A1 | NOVEL SULFONAMIDE DERIVATIVES HAVING SELECTIVE NOX INHIBITING ACTIVITY | NOX4, NOX1, NOX5 | MGAM 1703/4885HSD17B13 1827/4885ACLY 2249/4885 |
| US-20090176804-A1 | 2-PHENYL-INDOLES AS PROSTAGLANDIN D2 RECEPTOR ANTAGONISTS | PTGER2, PTGDR2, CYSLTR2 | MGAM 4301/4885HSD17B13 2206/4885ACLY 4136/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.