Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 1/20 | 0.48 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.48 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.45 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 6/20 | 0.40 |
| ▸ | ESR1 | P03372 | 4/20 | 0.40 |
| ▸ | USP7 | Q93009 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1146723 | 0.80 | ESR2 (0.53) | MMP3BCL2L1RPS6KA3ESR2ESR1 | |
| SCHEMBL27626561 | 0.80 | MMP3 (0.50) | MMP3BCL2L1RPS6KA3PDE4APDE4B | |
| SCHEMBL27607671 | 0.79 | MMP3 (0.48) | MMP3BCL2L1RPS6KA3PDE4APDE4B | |
| SCHEMBL27607682 | 0.79 | ESR2 (0.50) | MMP3BCL2L1RPS6KA3PDE4APDE4B | |
| SCHEMBL27607673 | 0.78 | ESR1 (0.46) | MMP3BCL2L1RPS6KA3PDE4APDE4B | |
| SCHEMBL27607687 | 0.76 | MMP3 (0.45) | MMP3BCL2L1RPS6KA3PDE4APDE4B | |
| SCHEMBL29546125 | 0.76 | HSD17B10 (0.50) | MEN1KMT2AKDM4EUSP2ALDH1A1 | |
| SCHEMBL25014 | 0.76 | HSD17B10 (0.50) | MEN1KMT2AKDM4EUSP2ALDH1A1 | |
| SCHEMBL9568350 | 0.75 | ALDH1A1 (0.38) | KMT2AALDH1A1LMNAMAPTHTT | |
| SCHEMBL2879057 | 0.75 | ALDH1A1 (0.38) | KMT2AALDH1A1LMNAMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1646478-A | 3-aminophenol derivatives substituted in the 2-position and colorants comprising the same | P & G CLAIROL INC (US) | 2005-07-27 | — | — | CN | claimed |
| CN-1646478-A | 3-aminophenol derivatives substituted in the 2-position and colorants comprising the same | P & G CLAIROL INC (US) | 2005-07-27 | — | — | CN | disclosed |