Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 6/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 6/20 | 0.46 |
| ▸ | MMP3 | P08254 | 1/20 | 0.44 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.44 |
| ▸ | KIF11 | P52732 | 2/20 | 0.44 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | USP7 | Q93009 | 4/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | FABP4 | P15090 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28187710 | 0.80 | KIF11 (0.50) | ESR1ESR2KIF11USP7FFAR4 | |
| SCHEMBL28756016 | 0.78 | MMP3 (0.48) | ESR1ESR2MMP3BCL2L1RPS6KA3 | |
| SCHEMBL4392007 | 0.78 | L3MBTL1 (0.42) | ESR1KIF11FABP4L3MBTL1ACHE | |
| SCHEMBL3781200 | 0.77 | FABP4 (0.47) | ESR1KIF11TDP1FABP4L3MBTL1 | |
| SCHEMBL1146723 | 0.76 | ESR2 (0.53) | ESR1ESR2MMP3BCL2L1RPS6KA3 | |
| SCHEMBL27626561 | 0.76 | MMP3 (0.50) | ESR1ESR2MMP3BCL2L1RPS6KA3 | |
| SCHEMBL27607671 | 0.75 | MMP3 (0.48) | ESR1ESR2MMP3BCL2L1RPS6KA3 | |
| SCHEMBL27607682 | 0.75 | ESR2 (0.50) | ESR1ESR2MMP3BCL2L1RPS6KA3 | |
| SCHEMBL27607687 | 0.72 | MMP3 (0.45) | ESR1ESR2MMP3BCL2L1RPS6KA3 | |
| SCHEMBL25014 | 0.72 | HSD17B10 (0.50) | TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1646478-A | 3-aminophenol derivatives substituted in the 2-position and colorants comprising the same | P & G CLAIROL INC (US) | 2005-07-27 | — | — | CN | claimed |
| CN-1646478-A | 3-aminophenol derivatives substituted in the 2-position and colorants comprising the same | P & G CLAIROL INC (US) | 2005-07-27 | — | — | CN | disclosed |