Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 1/20 | 0.48 |
| ▸ | AR | P10275 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 4/20 | 0.46 |
| ▸ | MAOB | P27338 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.43 |
| ▸ | TUBB | P07437 | 1/20 | 0.43 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30343916 | 0.82 | IMPDH2 (0.47) | MAPTPOLBGAAADORA2AADORA1 | |
| SCHEMBL25156188 | 0.82 | IMPDH2 (0.47) | MAPTPOLBGAAADORA2AADORA1 | |
| SCHEMBL5980999 | 0.81 | ESR2 (0.76) | PGRARESR1ESR2SMN1; SMN2 | |
| SCHEMBL27627326 | 0.80 | ESR2 (0.73) | ARESR1ESR2 | |
| SCHEMBL27627364 | 0.79 | ESR1 (0.48) | PGRARESR1ESR2CYP11B1 | |
| SCHEMBL2185402 | 0.79 | GPR84 (0.48) | ESR1ESR2KDM4EALDH1A1MAPT | |
| SCHEMBL13241111 | 0.78 | CYP1A2 (0.53) | KDM4EALDH1A1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL19919240 | 0.77 | ESR1 (0.49) | ESR1ESR2ALDH1A1MAPTHPGD | |
| SCHEMBL3014632 | 0.77 | PGR (0.52) | PGRARESR1ESR2KDM4E | |
| SCHEMBL312277 | 0.76 | SMN1; SMN2 (0.53) | ESR1ESR2KDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1738788-A | Substituted phenylnaphthalenes as estrogenic agents | WYETH CORP (US) | 2006-02-22 | — | — | CN | disclosed |