SCHEMBL28756705

SCHEMBL28756705

CC(C)(C)ON(C=O)CCCC(=O)c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.47
TDP1 Q9NUW8 2/20 0.47
LMNA P02545 1/20 0.47
MAPT P10636 1/20 0.47
KMT2A Q03164 4/20 0.46
HDAC1 Q13547 5/20 0.44
HDAC8 Q9BY41 5/20 0.44
HDAC3 O15379 1/20 0.44
HDAC4 P56524 1/20 0.44
HDAC7 Q8WUI4 1/20 0.44
HDAC2 Q92769 1/20 0.44
HDAC10 Q969S8 1/20 0.44
HDAC11 Q96DB2 1/20 0.44
HDAC6 Q9UBN7 1/20 0.44
HDAC9 Q9UKV0 1/20 0.44
HDAC5 Q9UQL6 1/20 0.44
NPC1 O15118 1/20 0.43
CASP3 P42574 1/20 0.43
RAB9A P51151 1/20 0.43
SENP8 Q96LD8 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL942894 0.92 KMT2A (0.53) L3MBTL1TDP1LMNAMAPTKMT2A
SCHEMBL941122 0.82 ALDH1A1 (0.43) L3MBTL1TDP1LMNAMAPTKMT2A
SCHEMBL4522063 0.79 SLC22A6 (0.39) TDP1LMNAKMT2AHDAC11MEN1
SCHEMBL3089829 0.74 L3MBTL1 (0.50) L3MBTL1TDP1LMNAMAPTKMT2A
SCHEMBL9866159 0.73 TSHR (0.40) TDP1LMNAKMT2AHDAC11MEN1
SCHEMBL6949347 0.73 TAAR1 (0.44) L3MBTL1TDP1KMT2ANPC1RAB9A
SCHEMBL1052631 0.73 TDP1 (0.86) L3MBTL1TDP1LMNAMAPTKMT2A
SCHEMBL6824194 0.72 KMT2A (0.67) L3MBTL1TDP1LMNAMAPTKMT2A
SCHEMBL3903619 0.72 TSHR (0.36) HDAC1HDAC8HDAC3HDAC2
SCHEMBL5741195 0.70 ALDH1A1 (0.41) MAPTKMT2ANR4A2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1802361-A M-stage kinesin inhibitor KYOWA HAKKO KOGYO KK (JP) 2006-07-12 CN disclosed