SCHEMBL2875690

SCHEMBL2875690

CCCC(Br)(Br)c1ccccc1C(Br)(Br)CCC

nearest known ligand 0.35

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 2/20 0.33
ESR2 Q92731 2/20 0.33
GAA P10253 1/20 0.32
ALOX12 P18054 1/20 0.32
CYP2C19 P33261 1/20 0.32
ALDH1A1 P00352 1/20 0.32
TSHR P16473 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
TP53 P04637 1/20 0.32
AR P10275 1/20 0.30
KCNN4 O15554 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2876018 0.85 ESR1 (0.38) ESR1ESR2GAACYP2C19TDP1
SCHEMBL4619728 0.84 TSHR (0.50) ESR1ESR2ALDH1A1TSHRTDP1
SCHEMBL2878770 0.83 GAA (0.38) GAACYP2C19ALDH1A1TSHRTP53
SCHEMBL2876406 0.81 LIPG (0.37) GAACYP2C19ALDH1A1TSHRTP53
SCHEMBL2878195 0.81 LIPG (0.37) GAACYP2C19ALDH1A1TSHRTP53
SCHEMBL6680536 0.81 ALDH1A1 (0.39) CYP2C19ALDH1A1TSHRTDP1
SCHEMBL2875372 0.78 TP53 (0.35) ALDH1A1TSHRTDP1TP53KCNN4
SCHEMBL6682083 0.77 KCNN4 (0.43) ESR1ESR2CYP2C19ALDH1A1TSHR
SCHEMBL5590121 0.77 ALDH1A1 (0.41) ESR1ESR2ALOX12ALDH1A1TSHR
SCHEMBL2877959 0.72 HSD17B10 (0.37) GAACYP2C19ALDH1A1TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100151392-A1 ANTIREFLECTIVE COATING COMPOSITIONS RAHMAN M DALIL 2010-06-17 US disclosed