SCHEMBL2878770

SCHEMBL2878770

CCCCCC(Br)(Br)c1ccccc1C(Br)(Br)CCCCC

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.38
LIPG Q9Y5X9 1/20 0.34
SIGMAR1 Q99720 1/20 0.34
LTA4H P09960 1/20 0.34
CNR2 P34972 2/20 0.33
TP53 P04637 2/20 0.33
TSHR P16473 2/20 0.33
MAPK1 P28482 2/20 0.33
ALDH1A1 P00352 2/20 0.33
CNR1 P21554 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C19 P33261 1/20 0.33
KCNH2 Q12809 1/20 0.33
CES2 O00748 1/20 0.33
CES1 P23141 1/20 0.33
DNM1 Q05193 1/20 0.33
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2876406 0.98 LIPG (0.37) GAALIPGCNR2TP53TSHR
SCHEMBL2878195 0.98 LIPG (0.37) GAALIPGCNR2TP53TSHR
SCHEMBL2876018 0.93 ESR1 (0.38) GAALIPGLTA4HCYP1A2CYP2C19
SCHEMBL9751192 0.85 ALDH1A1 (0.44) CNR2TSHRALDH1A1CNR1MEN1
SCHEMBL2875690 0.83 ESR1 (0.33) GAATP53TSHRALDH1A1CYP2C19
SCHEMBL6684254 0.83 KDM4E (0.38) GAACNR2MAPK1ALDH1A1CNR1
SCHEMBL6685429 0.82 KDM4E (0.39) GAACNR2MAPK1ALDH1A1CNR1
SCHEMBL6681394 0.82 KDM4E (0.39) GAACNR2MAPK1ALDH1A1CNR1
SCHEMBL6689783 0.80 SIGMAR1 (0.41) GAASIGMAR1LTA4HCES2CES1
SCHEMBL5586714 0.79 ALDH1A1 (0.40) CNR2ALDH1A1CNR1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100151392-A1 ANTIREFLECTIVE COATING COMPOSITIONS RAHMAN M DALIL 2010-06-17 US disclosed