SCHEMBL28757237

SCHEMBL28757237

S=Cc1cccc2c1C=CC2

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2860485 0.80 MEN1 (0.41) CA1CA2
SCHEMBL29561529 0.80 MEN1 (0.41) CA1CA2
SCHEMBL7636146 0.80 ALDH1A1 (0.34) CA1CA2
SCHEMBL6533122 0.74 NFE2L2 (0.47)
SCHEMBL22669111 0.74
SCHEMBL277191 0.70 CA1 (0.33) CA1CA2
SCHEMBL1324313 0.68 CA1 (0.32) CA1CA2
SCHEMBL277192 0.68 BCL2L1 (0.39) CA1CA2
SCHEMBL13374382 0.68 CA1 (0.32) CA1CA2
SCHEMBL2783384 0.68 CA1 (0.32) CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101152185-B Use of heterocyclic compounds as SCCE inhibitors AREXIS AB 2010-12-08 CN disclosed
CN-100518740-C Pharmaceutical use of heterocyclic compounds as SCCE inhibitors AREXIS AB (SE) 2009-07-29 CN disclosed
CN-101152185-A Use of heterocyclic compounds as scce inhibitors AREXIS AB (SE) 2008-04-02 CN disclosed
CN-1802160-A Use of heterocyclic compounds as SCCE inhibitors AREXIS AB (SE) 2006-07-12 CN disclosed