SCHEMBL277192

SCHEMBL277192

Oc1cccc2c1C=CC2

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCL2L1 Q07817 1/20 0.39
BAD Q92934 1/20 0.39
ALDH1A1 P00352 3/20 0.38
ALOX15 P16050 3/20 0.38
HSD17B10 Q99714 3/20 0.38
TDP1 Q9NUW8 3/20 0.38
CYP3A4 P08684 2/20 0.38
MAPT P10636 2/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
TSHR P16473 2/20 0.38
MEN1 O00255 1/20 0.38
USP2 O75604 1/20 0.38
HPN P05981 1/20 0.38
ALOX5 P09917 1/20 0.38
THRB P10828 1/20 0.38
PTGS1 P23219 1/20 0.38
PDE4A P27815 1/20 0.38
KDR P35968 1/20 0.38
KMT2A Q03164 1/20 0.38
SIRT5 Q9NXA8 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30042387 1.00 BCL2L1 (0.39) BCL2L1BADALDH1A1ALOX15HSD17B10
Hydrochloric Acid SCHEMBL28866187 0.98 BCL2L1 (0.38) BCL2L1BADALDH1A1ALOX15HSD17B10
SCHEMBL4445125 0.78 BCL2L1 (0.41) BCL2L1BADALDH1A1ALOX15HSD17B10
SCHEMBL7450666 0.78 BCL2L1 (0.36) BCL2L1BADALDH1A1ALOX15HSD17B10
SCHEMBL2783384 0.77 CA1 (0.32) CA2CA1
SCHEMBL30183336 0.77 CA1 (0.32) CA2CA1
SCHEMBL23668366 0.77 CYP3A4 (0.41) ALDH1A1HSD17B10CYP3A4MAPTTSHR
Lithium SCHEMBL29767672 0.76 CA1 (0.32) CA2CA1
SCHEMBL28432571 0.76 CA1 (0.32) CA2CA1
SCHEMBL277191 0.74 CA1 (0.33) CA2CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 216 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105732307-B The synthetic method of Maxacalcitol intermediate 科贝源(北京)生物医药科技有限公司 2019-04-19 CN claimed
CN-105209429-B SHIP1 conditioning agents and relative method 阿奎诺克斯药物(加拿大)公司 2018-05-29 CN claimed
US-20250241872-A1 AFFINITY MEDICANT CONJUGATE Illudent, Inc. (US) 2025-07-31 US disclosed
US-12280021-B2 Affinity medicant conjugate AF CHEMICALS, LLC (US) 2025-04-22 US disclosed
US-20230372267-A1 AFFINITY MEDICANT CONJUGATE Califia Pharma Inc. (US) 2023-11-23 US disclosed
US-20230159766-A1 CONDUCTIVE POLYMER COMPOSITION, SUBSTRATE, AND METHOD FOR PRODUCING SUBSTRATE SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-05-25 US disclosed
US-11576876-B2 Affinity Medicant Conjugate AF CHEMICALS, LLC (US) 2023-02-14 US disclosed
US-20220133649-A1 AFFINITY MEDICANT CONJUGATE Califia Pharma Inc. (US) 2022-05-05 US disclosed
US-20210380738-A1 CONDUCTIVE POLYMER COMPOSITION, SUBSTRATE, AND METHOD FOR PRODUCING SUBSTRATE SHIN-ETSU CHEMICAL CO., LTD. (JP) 2021-12-09 US disclosed
CN-112105654-A Curable resin mixture, curable resin composition, and cured product thereof 日本化药株式会社 2020-12-18 CN disclosed
US-20200259094-A1 CONDUCTIVE POLYMER COMPOSITE AND CONDUCTIVE POLYMER COMPOSITION SHIN-ETSU CHEMICAL CO., LTD. (JP) 2020-08-13 US disclosed
WO-2004108683-A1 3-ALKYLIDENEHYDRAZINO SUBSTITUTED HETEROARYL COMPOUNDS AS THROMBOPOIETIN RECEPTOR ACTIVATORS NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2004-12-16 WO disclosed
CN-1538975-A Metallocene catalysts containing idenyl moiety substituted at the 4-5-6-or 7-position by siloxy or germyloxy group 2004-10-20 CN disclosed
US-20040152882-A1 Metallocene catalysts containing an idenyl moiety substituted at the 4,-5,-6- or 7-position by a siloxy or germyloxy group BOREALIS TECHNOLOGY OY (FI) 2004-08-05 US disclosed
CN-1516690-A Heterocyclic derivatives and medicines �ձ���ҩ��ʽ���� 2004-07-28 CN disclosed
EP-1401880-A1 METALLOCENE CATALYSTS CONTAINING AN INDENYL MOIETY SUBSTITUTED AT THE 4-, 5-, 6- OR 7-POSITION BY A SILOXY OR GERMYLOXY GROUP Borealis Technology Oy (FI) 2004-03-31 EP disclosed
WO-2003000744-A1 METALLOCENE CATALYSTS CONTAINING AN IDENYL MOIETY SUBSTITUTED AT THE 4-, 5-, 6- OR 7-POSITION BY A SILOXY OR GERMYLOXY GROUP BOREALIS TECHNOLOGY OY (FI) 2003-01-03 WO disclosed
US-4435397-A ADRENERGIC BLOCKING AGENTS, 4-(3-ARYLOXY-2-HYDROXYPROPYL) SUBSTITUTED NIPPON SHINYAKU CO., LTD. (JP) 1984-03-06 US disclosed
US-4127675-A BETA-RECEPTOR ANTAGONISTS YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) 1978-11-28 US disclosed
US-4045482-A ADRENERGIC B-RECEPTOR BLOCKING AGENTS YAMANOUCHI PHARMACEUTICAL CO. LTD. (JA) 1977-08-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12280021-B2 Affinity medicant conjugate FCER2, HDGF, FCGR2A BCL2L1 1011/4885BAD 594/4885ALDH1A1 3966/4885
US-20230372267-A1 AFFINITY MEDICANT CONJUGATE FCER2, HDGF, FCGR2A BCL2L1 1011/4885BAD 594/4885ALDH1A1 3966/4885
US-20220133649-A1 AFFINITY MEDICANT CONJUGATE FCER2, HDGF, FCGR2A BCL2L1 1011/4885BAD 594/4885ALDH1A1 3966/4885
US-20040152882-A1 Metallocene catalysts containing an idenyl moiety substituted at the 4,-5,-6- or 7-position by a siloxy or germyloxy group IPO4, GEMIN4, GEMIN5 BCL2L1 2789/4885BAD 3791/4885ALDH1A1 1415/4885
US-11576876-B2 Affinity Medicant Conjugate FCER2, HDGF, FCGR2A BCL2L1 1011/4885BAD 594/4885ALDH1A1 3966/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.