Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K7 | O14733 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1638186 | 0.85 | CRHR1 (0.39) | MAP2K7CHRM3PDE4APDE4BPDE4C | |
| SCHEMBL1637789 | 0.84 | CHRM3 (0.34) | MAP2K7CHRM3PDE4APDE4BPDE4C | |
| SCHEMBL1638401 | 0.80 | KDM4E (0.32) | MAP2K7CHRM3PDE4APDE4BPDE4C | |
| SCHEMBL13890557 | 0.79 | KDM4E (0.31) | CHRM3PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL1636123 | 0.79 | CHRM3 (0.31) | CHRM3PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL13890692 | 0.78 | CRHR1 (0.33) | CHRM3PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL1637158 | 0.78 | CRHR1 (0.33) | CHRM3PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL13890657 | 0.77 | FPR3 (0.30) | — | |
| SCHEMBL1637882 | 0.76 | CRHR1 (0.33) | CHRM3PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL27613657 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1692115-A | Pyrrolopyrimidine and pyrrolopyridine derivatives substituted with cyclic amino group | TAISHO PHARMACEUTICAL CO LTD (JP) | 2005-11-02 | — | — | CN | claimed |
| CN-1692115-A | Pyrrolopyrimidine and pyrrolopyridine derivatives substituted with cyclic amino group | TAISHO PHARMACEUTICAL CO LTD (JP) | 2005-11-02 | — | — | CN | disclosed |