SCHEMBL28757459

SCHEMBL28757459

Oc1ccc(-c2ccc(-c3ccccc3-c3ccccc3)c(O)c2)cc1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 3/20 0.59
BCL2L1 Q07817 2/20 0.58
MMP3 P08254 1/20 0.58
ABL1 P00519 2/20 0.57
ABCB1 P08183 2/20 0.57
BCR P11274 2/20 0.57
ESR1 P03372 4/20 0.54
MEN1 O00255 3/20 0.54
KMT2A Q03164 3/20 0.54
ESR2 Q92731 4/20 0.50
BACE1 P56817 1/20 0.50
HSD17B1 P14061 1/20 0.50
HSD17B2 P37059 1/20 0.50
APP P05067 1/20 0.50
EGFR P00533 1/20 0.49
HTT P42858 2/20 0.48
RAB9A P51151 2/20 0.48
APAF1 O14727 1/20 0.48
NPC1 O15118 1/20 0.48
LMNA P02545 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31601680 0.90 ALOX5 (0.72) ALOX5BCL2L1MMP3ABL1ABCB1
SCHEMBL28118263 0.86 MMP3 (0.65) ALOX5BCL2L1MMP3ABL1ABCB1
SCHEMBL28132374 0.86 MMP3 (0.65) ALOX5BCL2L1MMP3ABL1ABCB1
SCHEMBL16581499 0.86 MMP3 (0.65) ALOX5BCL2L1MMP3ABL1ABCB1
SCHEMBL5523942 0.86 MMP3 (0.65) ALOX5BCL2L1MMP3ABL1ABCB1
SCHEMBL28229473 0.86 ALOX5 (0.79) ALOX5BCL2L1MMP3ABL1ABCB1
SCHEMBL340484 0.85 ALOX5 (0.73) ALOX5BCL2L1MMP3ESR1MEN1
SCHEMBL29786722 0.84 ALOX5 (0.63) ALOX5BCL2L1MMP3ABL1ABCB1
SCHEMBL7520745 0.84 ALOX5 (0.64) ALOX5BCL2L1MMP3ESR1MEN1
SCHEMBL1005885 0.83 ALOX5 (0.70) ALOX5BCL2L1MMP3ESR1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1721404-A Flame retardant resin blends based on polymers GEN ELECTRIC (US) 2006-01-18 CN claimed
CN-1721404-A Flame retardant resin blends based on polymers GEN ELECTRIC (US) 2006-01-18 CN disclosed