SCHEMBL1005885

SCHEMBL1005885

Oc1cc(-c2ccccc2)ccc1-c1ccccc1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.70
BACE1 P56817 1/20 0.64
EGFR P00533 2/20 0.62
ALDH1A1 P00352 2/20 0.61
HPGD P15428 2/20 0.61
HSD17B10 Q99714 2/20 0.61
BCL2L1 Q07817 2/20 0.61
ACMSD Q8TDX5 3/20 0.57
HNF4A P41235 2/20 0.57
ESR2 Q92731 4/20 0.56
MEN1 O00255 2/20 0.56
LMNA P02545 2/20 0.56
MAPT P10636 2/20 0.56
HTT P42858 2/20 0.56
KMT2A Q03164 2/20 0.56
KDM4E B2RXH2 1/20 0.56
USP2 O75604 1/20 0.56
HSP90AA1 P07900 1/20 0.56
GAA P10253 1/20 0.56
ALOX15 P16050 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31601680 0.93 ALOX5 (0.72) ALOX5BACE1EGFRALDH1A1HPGD
SCHEMBL340484 0.92 ALOX5 (0.73) ALOX5BACE1EGFRALDH1A1HPGD
SCHEMBL22539594 0.89 EGFR (0.58) ALOX5BACE1EGFRALDH1A1HPGD
Sulfur Dioxide SCHEMBL27208990 0.89 ALOX5 (0.59) ALOX5BACE1EGFRALDH1A1HPGD
SCHEMBL1180810 0.87 ALOX5 (0.69) ALOX5BACE1EGFRALDH1A1HPGD
SCHEMBL7789645 0.86 EGFR (0.69) ALOX5EGFRHSD17B10ACMSDHNF4A
SCHEMBL7520745 0.86 ALOX5 (0.64) ALOX5BACE1EGFRALDH1A1HPGD
SCHEMBL22280682 0.86 ALOX5 (0.91) ALOX5BACE1EGFRALDH1A1HPGD
SCHEMBL29206155 0.84 EGFR (0.54) ALOX5BACE1EGFRALDH1A1HPGD
SCHEMBL14283895 0.84 BACE1 (0.89) ALOX5BACE1EGFRALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 76 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0420619-A2 Engineering plastic composition and articles made of the same SEKISUI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1991-04-03 EP claimed
US-12421349-B2 Polyphenylene ether composition ASAHI KASEI KABUSHIKI KAISHA (JP) 2025-09-23 US disclosed
CN-114514261-B Polyphenylene ether composition 旭化成株式会社 2024-09-10 CN disclosed
CN-117229495-A Polyphenylene ether, method for producing the same, thermosetting composition, prepreg, and laminate 旭化成株式会社 2023-12-15 CN disclosed
EP-4039728-B1 POLYPHENYLENE ETHER COMPOSITION ASAHI CHEMICAL IND (JP) 2023-10-11 EP disclosed
CN-112812291-B Hydrogenated polyphenylene ether and process for producing the same 旭化成株式会社 2023-07-18 CN disclosed
WO-2023127934-A1 ENERGY-RAY-CURABLE COMPOSITION FOR THREE-DIMENSIONAL SHAPING USE, DENTAL STRUCTURE, MOUTHPIECE, TEETH-STRAIGHTENING MOUTHPIECE, AND METHOD FOR PRODUCING DENTAL STRUCTURE クラレノリタケデンタル株式会社 2023-07-06 WO disclosed
US-20230172059-A1 LIGHT EMITTING ELEMENT AND AMINE COMPOUND FOR THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2023-06-01 US disclosed
US-20230172059-A1 LIGHT EMITTING ELEMENT AND AMINE COMPOUND FOR THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2023-06-01 US disclosed
US-20230172059-A1 LIGHT EMITTING ELEMENT AND AMINE COMPOUND FOR THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2023-06-01 US disclosed
US-20060122420-A1 Process for producing aromatic hydroxycarboxylic acids CHIBA INSTITUTE OF TECHNOLOGY 2006-06-08 US disclosed
WO-2005100301-A1 2-ARYLOXYETHYL GLYCINE DERIVATIVES AND THEIR USE AS GLYCINE TRANSPORT INHIBITORS ELI LILLY AND COMPANY (US) 2005-10-27 WO disclosed
EP-1160267-B1 CATALYST FOR OXIDATIVE POLYMERIZATION OF FLUOROPHENOL, METHOD OF OXIDATIVE POLYMERIZATION OF FLUOROPHENOL, AND POLY(OXYFLUOROPHENYLENE) DERIVATIVE JAPAN SCIENCE & TECH CORP (JP) 2004-08-04 EP disclosed
US-6689919-B1 SOLUBLE POLY(OXYFLUOROPHENYLENE) COMPOUNDS WITH EXCELLENT HEAT RESISTANCE, MEMBRANE-FORMABILITY AND CHEMICAL STABILITY JAPAN SCIENCE AND TECHNOLOGY CORPORATION (JP) 2004-02-10 US disclosed
US-6486359-B1 Catalyst comprising a complex of a metal of subgroup viii based on a phosphinite ligand, and a method for hydroformylation BASF AKTIENGESELLSCHAFT (DE) 2002-11-26 US disclosed
EP-1160267-A1 CATALYST FOR OXIDATIVE POLYMERIZATION OF FLUOROPHENOL, METHOD OF OXIDATIVE POLYMERIZATION OF FLUOROPHENOL, AND POLY(OXYFLUOROPHENYLENE) DERIVATIVE Japan Science and Technology Corporation (JP) 2001-12-05 EP disclosed
EP-0337175-B1 ELECTROCHEMICAL SYNTHESIS OF 2-ARYL-HYDROQUINONES MINISTERO DELL' UNIVERSITA' E DELLA RICERCA SCIENTIFICA E TECNOLOGICA (IT) 1993-05-19 EP disclosed
US-5098531-A ELECTROCHEMICAL SYNTHESIS OF 2-ARYL-HYDROQUINONES ISTITUTO GUIDO DONEGANI S.P.A. (IT) 1992-03-24 US disclosed
EP-0337175-A1 Electrochemical synthesis of 2-aryl-hydroquinones MINISTERO DELL' UNIVERSITA' E DELLA RICERCA SCIENTIFICA E TECNOLOGICA (IT) 1989-10-18 EP disclosed
US-4692555-A Preparation of diphenolics ETHYL CORPORATION (US) 1987-09-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230172059-A1 LIGHT EMITTING ELEMENT AND AMINE COMPOUND FOR THE SAME ESR1, NFE2L2, LAGE3 ALOX5 1277/4885BACE1 528/4885EGFR 1496/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.