Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | CES2 | O00748 | 3/20 | 0.50 |
| ▸ | CES1 | P23141 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9740694 | 0.85 | LMNA (0.52) | LMNACES2CES1MAPK1ALDH1A1 | |
| SCHEMBL972915 | 0.79 | LMNA (0.57) | LMNACES2CES1MAPK1ALDH1A1 | |
| SCHEMBL28331328 | 0.78 | CES2 (0.52) | LMNACES2CES1MAPK1ALDH1A1 | |
| SCHEMBL28831101 | 0.75 | LMNA (0.49) | LMNACES2CES1MAPK1ALDH1A1 | |
| SCHEMBL28271166 | 0.74 | CES2 (0.47) | LMNACES2CES1MAPK1ALDH1A1 | |
| SCHEMBL28137733 | 0.72 | CES2 (0.49) | LMNACES2CES1MAPK1ALDH1A1 | |
| SCHEMBL27428737 | 0.72 | CES2 (0.49) | LMNACES2CES1MAPK1ALDH1A1 | |
| SCHEMBL30783688 | 0.72 | LMNA (0.49) | LMNACES2CES1MAPK1ALDH1A1 | |
| SCHEMBL28868999 | 0.72 | CES2 (0.50) | LMNACES2CES1MAPK1ALDH1A1 | |
| SCHEMBL17956155 | 0.72 | LMNA (0.45) | LMNACES2CES1MAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106187758-A | A kind of synthetic method of the different monooctyl ester of tetrabromobenzoic acid | 潍坊玉成化工有限公司 | 2016-12-07 | — | — | CN | disclosed |
| CN-106187758-A | A kind of synthetic method of the different monooctyl ester of tetrabromobenzoic acid | 潍坊玉成化工有限公司 | 2016-12-07 | — | — | CN | disclosed |
| CN-1819988-B | Method for producing tetrabromobenzoate ester | GREAT LAKES CHEMICAL CORP | 2010-12-08 | — | — | CN | disclosed |
| CN-101805262-A | Produce the method for tetrabromo benzoate | GREAT LAKES CHEMICAL CORP | 2010-08-18 | — | — | CN | disclosed |
| CN-1819988-A | Method for producing tetrabromobenzoate ester | GREAT LAKES CHEMICAL CORP (US) | 2006-08-16 | — | — | CN | disclosed |