SCHEMBL972915

SCHEMBL972915

O=C(c1ccccc1Br)C(O)c1ccccc1

nearest known ligand 0.57

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.57
CES2 O00748 3/20 0.57
CES1 P23141 3/20 0.57
MAPK1 P28482 1/20 0.52
ALDH1A1 P00352 3/20 0.49
KDM4E B2RXH2 1/20 0.45
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
TDP1 Q9NUW8 2/20 0.44
SRC P12931 1/20 0.43
HPGD P15428 3/20 0.43
POLB P06746 1/20 0.40
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28331328 0.87 CES2 (0.52) LMNACES2CES1MAPK1ALDH1A1
SCHEMBL28137733 0.84 CES2 (0.49) LMNACES2CES1MAPK1ALDH1A1
SCHEMBL27428737 0.84 CES2 (0.49) LMNACES2CES1MAPK1ALDH1A1
SCHEMBL11226878 0.82 ALDH1A1 (0.59) LMNACES2CES1MAPK1ALDH1A1
SCHEMBL30783688 0.81 LMNA (0.49) LMNACES2CES1MAPK1ALDH1A1
SCHEMBL28831101 0.81 LMNA (0.49) LMNACES2CES1MAPK1ALDH1A1
SCHEMBL28827502 0.81 LMNA (0.45) LMNACES2CES1MAPK1ALDH1A1
SCHEMBL9740694 0.80 LMNA (0.52) LMNACES2CES1MAPK1ALDH1A1
SCHEMBL10428607 0.80 LMNA (0.61) LMNACES2CES1MAPK1ALDH1A1
SCHEMBL28271166 0.80 CES2 (0.47) LMNACES2CES1MAPK1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3041627-A1 METAL SINTERING FILM COMPOSITIONS Henkel IP & Holding GmbH (DE) 2016-07-13 EP claimed
CN-1678325-A Sapogenin derivatives, their synthesis and use and method based upon the use PHYTOTECH LTD (GB) 2005-10-05 CN claimed
EP-0947521-B1 Removal of dissolved silicates from alcohol-silicon direct synthesis solvents CROMPTON CORP (US) 2003-03-19 EP claimed
EP-0788314-B1 NONDIGESTIBLE FAT COMPOSITIONS CONTAINING DIVERSELY ESTERIFIED POLYOL POLYESTERS FOR PASSIVE OIL LOSS CONTROL PROCTER & GAMBLE (US) 2001-09-12 EP claimed
US-6090965-A Removal of dissolved silicates from alcohol-silicon direct synthesis solvents OSI SPECIALTIES, INC. (US) 2000-07-18 US claimed
EP-0947521-A2 Removal of dissolved silicates from alcohol-silicon direct synthesis solvents WITCO CORPORATION (US) 1999-10-06 EP claimed
EP-0788314-A1 NONDIGESTIBLE FAT COMPOSITIONS CONTAINING DIVERSELY ESTERIFIED POLYOL POLYESTERS FOR PASSIVE OIL LOSS CONTROL THE PROCTER & GAMBLE COMPANY (US) 1997-08-13 EP claimed
US-5480667-A CONTAING NONDIGESTIBLE SOLID POLYOL ESTERS OF SPECIFIED CARBON CHAIN LENGTH FATTY ACID DISPERSED IN LIQUID NONDIGESTIBLE OIL; POTATO CHIPS CORRIGAN PATRICK J (US) 1996-01-02 US claimed
US-5350790-A Aromatic carboxylic acid MITSUBISHI KASEI CORPORATION (JP) 1994-09-27 US claimed
WO-1994009639-A1 NONDIGESTIBLE FAT COMPOSITIONS CONTAINING DIVERSELY ESTERIFIED POLYOL POLYESTERS FOR PASSIVE OIL LOSS CONTROL THE PROCTER & GAMBLE COMPANY (US) 1994-05-11 WO claimed
US-4150206-A SYNERGISTIC CATALYSTS S.A. PRB (BE) 1979-04-17 US claimed
CN-118900677-A Dental adhesive composition 株式会社GC 2024-11-05 CN disclosed
US-20200165300-A1 Cyclic Peptides Targeting Alpha-4-Beta-7 Integrin ZEALAND PHARMA A/S (DK) 2020-05-28 US disclosed
CN-110832039-A Dielectric ink composition 阿尔法装配解决方案公司 2020-02-21 CN disclosed
CN-110776583-A Method for synthesizing active bagasse xylan p-bromobenzoic acid/cinnamic acid diester 桂林理工大学 2020-02-11 CN disclosed
US-4328111-A CORROSION INHIBITION STANDARD OIL COMPANY (INDIANA) (US) 1982-05-04 US disclosed
US-4150206-A SYNERGISTIC CATALYSTS S.A. PRB (BE) 1979-04-17 US disclosed
US-4107210-A Synthesis of alpha-diketones THE DOW CHEMICAL COMPANY (US) 1978-08-15 US disclosed
US-4032550-A IMMOBILIZED SUPPORTED TRANSITION METAL CATALYST EMERY INDUSTRIES, INC. (US) 1977-06-28 US disclosed
US-3945991-A Heterocyclic azo compounds containing a quaternated hydrazide group CIBA-GEIGY AG (CH) 1976-03-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200165300-A1 Cyclic Peptides Targeting Alpha-4-Beta-7 Integrin ITGB7, ITGB4, ITGA4 LMNA 1539/4885CES2 4171/4885CES1 3003/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.