Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.41 |
| ▸ | TDP2 | O95551 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 4/20 | 0.37 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.36 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.36 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.36 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.36 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27622003 | 0.82 | CYP3A4 (0.44) | MAPTNPC1KDM1ACYP11B1CYP11B2 | |
| SCHEMBL27641107 | 0.82 | TDP2 (0.40) | TDP2ALOX5NTRK2HSD17B3CYP1A2 | |
| SCHEMBL27640949 | 0.78 | ABL1 (0.43) | KDM4ENPC1ALDH1A1CYP11B1CYP11B2 | |
| SCHEMBL27622023 | 0.78 | HRH3 (0.48) | MAOB | |
| SCHEMBL22073568 | 0.72 | MAOA (0.41) | PARP10PARP11TDP2KDM4EMEN1 | |
| SCHEMBL5254986 | 0.72 | PARP10 (0.49) | PARP10PARP11TDP2ALOX5KDM4E | |
| SCHEMBL9489772 | 0.72 | HRH3 (0.43) | MEN1MAPTKMT2AGAAKDM1A | |
| SCHEMBL6253369 | 0.72 | HSD17B3 (0.51) | PARP10PARP11TDP2ALOX5KDM4E | |
| SCHEMBL2680 | 0.71 | — | — | |
| SCHEMBL9443952 | 0.71 | CYP2A6 (0.39) | NPC1ALDH1A1CYP11B2ESR2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1735408-A | Receptor function controlling agent | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2006-02-15 | — | — | CN | disclosed |